ArticleMolecular and cellular biochemistry2001
Receptor-Ck regulates membrane-bound 125 kDa protein having affinity for genomic sterol regulatory sequence.
Article in Molecular and cellular biochemistry, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 3 citations in OpenAlex.
- Giardia lamblia low-density lipoprotein receptor-related protein is involved in selective lipoprotein endocytosis and parasite replication.Molecular microbiology · 2011Article
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2 authors at 1 institution in 1 country.
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Abstract
The study addressed, to resolve the role of Receptor-Ck activation in the proteolytic maturation of 125 kDa (membrane bound) sterol regulatory element binding protein (SREBP), revealed that Receptor-Ck dependent signalling is not only responsible for the proteoloytic cleavage of this 125 kDa SREBP resulting in the generation of an active 47 kDa factor but also Receptor-Ck protein has high binding affinity for both 125 kDa SREBP as well as its cleaved 47 kDa product. Based upon these coupled with our earlier findings, we propose that Receptor-Ck may be regulating genes, have sterol regulatory element (SRE) in their promoter region, through the proteolytic maturation of 125 kDa SREBP into an active 47 kDa transcription factor.
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