ReviewEndocrine2000
Growth hormone: roles in male reproduction.
Review in Endocrine, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 66 citations in OpenAlex.
- Pituitary crosstalk with bone, adipose tissue and brain.Nature reviews. Endocrinology · 2023Review
- Effects of Growth Hormone on Adult Human Gonads: Action on Reproduction and Sexual Function.International journal of endocrinology · 2023Review
- Evaluation of sex hormone profile and semen parameters in acromegalic male patients.Journal of endocrinological investigation · 2021Article
- CBX2-dependent transcriptional landscape: implications for human sex development and its defects.Scientific reports · 2019Article
- The wonders of BMP9: From mesenchymal stem cell differentiation, angiogenesis, neurogenesis, tumorigenesis, and metabolism to regenerative medicine.Genes & diseases · 2019Review
- Growth Hormone and Insulin-Like Growth Factor Action in Reproductive Tissues.Frontiers in endocrinology · 2019Review
- Multiple Effects of Growth Hormone in the Body: Is it Really the Hormone for Growth?Clinical medicine insights. Endocrinology and diabetes · 2016Review
- Insulin-like factor 3 plasma levels in acromegaly before and after somatostatin analog treatment.Endocrine · 2015Article
- Growth hormone and reproduction: a review of endocrine and autocrine/paracrine interactions.International journal of endocrinology · 2014Review
- Differential regulation of Kit ligand A expression in the ovary by IGF-I via different pathways.Molecular endocrinology (Baltimore, Md.) · 2014Article
- BMP signaling in mesenchymal stem cell differentiation and bone formation.Journal of biomedical science and engineering · 2013Article
- BMP9 signaling in stem cell differentiation and osteogenesis.American journal of stem cells · 2013Article
- Extrapituitary growth hormone.Endocrine · 2010Review
- Growth hormone is produced within the hippocampus where it responds to age, sex, and stress.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Growth hormone (GH), as its name suggests, is obligatory for growth and development. It is, however, also required for sexual differentiation and pubertal maturation and participates in gonadal steroidogenesis and gametogenesis. These roles are likely to reflect the endocrine actions of pituitary GH, directly at gonadal sites and indirectly via hepatic insulin-like growth factor-1. However, because GH is also produced in gonadal tissues, it may act in paracrine or autocrine ways to regulate local processes that are strategically regulated by pituitary GH. The concept that GH is a major regulator of male reproduction is the focus of this review.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.