ArticleProceedings of the National Academy of Sciences of the United States of America2001
Mitochondrial DNA sequences in ancient Australians: Implications for modern human origins.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.
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24 citing papers in PubMed, 225 citations in OpenAlex.
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- Ancient nuclear genomes enable repatriation of Indigenous human remains.Science advances · 2018Article
- Toward high-resolution population genomics using archaeological samples.DNA research : an international journal for rapid publication of reports on genes and genomes · 2016Review
- Denisovans, Melanesians, Europeans, and Neandertals: The Confusion of DNA Assumptions and the Biological Species Concept.Journal of molecular evolution · 2016Article
- Ancient mtDNA sequences from the First Australians revisited.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- A Comparison and Integration of MiSeq and MinION Platforms for Sequencing Single Source and Mixed Mitochondrial Genomes.PloS one · 2016Article
- Cultural inter-population differences do not reflect biological distances: an example of interdisciplinary analysis of populations from Eastern Adriatic coast.Croatian medical journal · 2015Article
- Introduction. Ancient DNA: the first three decades.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015Article
- Aspects of ancient mitochondrial DNA analysis in different populations for understanding human evolution.Balkan journal of medical genetics : BJMG · 2014Review
- Monitoring DNA contamination in handled vs. directly excavated ancient human skeletal remains.PloS one · 2013Article
- Socially responsible genetic research with descendants of the First Australians.Investigative genetics · 2012Article
- The RHNumtS compilation: features and bioinformatics approaches to locate and quantify Human NumtS.BMC genomics · 2008Article
- Evidence of authentic DNA from Danish Viking Age skeletons untouched by humans for 1,000 years.PloS one · 2008Article
- Cryptic contamination and phylogenetic nonsense.PloS one · 2008Article
- Evaluating Neanderthal genetics and phylogeny.Journal of molecular evolution · 2007Article
- Ancient DNA.Proceedings. Biological sciences · 2005Review
- How many clones need to be sequenced from a single forensic or ancient DNA sample in order to determine a reliable consensus sequence?Nucleic acids research · 2005Article
- No evidence of Neandertal mtDNA contribution to early modern humans.PLoS biology · 2004Article
- Evidence for a genetic discontinuity between Neandertals and 24,000-year-old anatomically modern Europeans.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
Corrections and comments
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- Erratum issued
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA from ancient human remains provides perspectives on the origin of our species and the relationship between molecular and morphological variation. We report analysis of mtDNA from the remains of 10 ancient Australians. These include the morphologically gracile Lake Mungo 3 [ approximately 60 thousand years (ka) before present] and three other gracile individuals from Holocene deposits at Willandra Lakes (<10 ka), all within the skeletal range of living Australians, and six Pleistocene/early Holocene individuals (15 to <8 ka) from Kow Swamp with robust morphologies outside the skeletal range of contemporary indigenous Australians. Lake Mungo 3 is the oldest (Pleistocene) "anatomically modern" human from whom DNA has been recovered. His mtDNA belonged to a lineage that only survives as a segment inserted into chromosome 11 of the nuclear genome, which is now widespread among human populations. This lineage probably diverged before the most recent common ancestor of contemporary human mitochondrial genomes. This timing of divergence implies that the deepest known mtDNA lineage from an anatomically modern human occurred in Australia; analysis restricted to living humans places the deepest branches in East Africa. The other ancient Australian individuals we examined have mtDNA sequences descended from the most recent common ancestor of living humans. Our results indicate that anatomically modern humans were present in Australia before the complete fixation of the mtDNA lineage now found in all living people. Sequences from additional ancient humans may further challenge current concepts of modern human origins.
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