What is the cause of lymphopenia in malaria?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

32 citing papers in PubMed, 55 citations in OpenAlex.

1. Overview of the host immune response toJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025
   Review
2. Comparative Analysis of Initial Full Blood Count Parameters in Adults Infected WithOpen forum infectious diseases · 2025
   Article
3. Haematological abnormalities as diagnostic indicators of malaria in returning travellers: a retrospective study at Mohamed V Military Instruction Hospital.Access microbiology · 2025
   Article
4. Evaluation of immunophenotypic alterations of peripheral blood lymphocytes and their sub-sets in uncomplicated P. Falciparum infection.BMC immunology · 2024
   Article
5. SARS-CoV-2-associated lymphopenia: possible mechanisms and the role of CD147.Cell communication and signaling : CCS · 2024
   Review
6. Immunogenomic profile at baseline predicts host susceptibility to clinical malaria.Frontiers in immunology · 2023
   Article
7. Clinical Progression ofPathogens (Basel, Switzerland) · 2022
   Article
8. The Contribution of Human Herpes Viruses to γδ T Cell Mobilisation in Co-Infections.Viruses · 2021
   Review
9. Total parasite biomass but not peripheral parasitaemia is associated with endothelial and haematological perturbations ineLife · 2021
   Article
10. Development and evaluation of a new Plasmodium falciparum 3D7 blood stage malaria cell bank for use in malaria volunteer infection studies.Malaria journal · 2021
    Article
11. Antimalarial and Erythrocyte Membrane Stability Properties ofInfection and drug resistance · 2021
    Article
12. Expansion of Functional Myeloid-Derived Suppressor Cells in Controlled Human Malaria Infection.Frontiers in immunology · 2021
    Article
13. Methnaridine is an orally bioavailable, fast-killing and long-acting antimalarial agent that cures Plasmodium infections in mice.British journal of pharmacology · 2020
    Article
14. Prevalence of malarial recurrence and hematological alteration following the initial drug regimen: a retrospective study in Western Thailand.BMC public health · 2019
    Article
15. HIV infection compounds the lymphopenia associated with cerebral malaria in Malawian children.Journal of blood medicine · 2019
    Article
16. Evaluating antidisease immunity to malaria and implications for vaccine design.Immunology · 2018
    Review
17. Lymphocytosis and Lymphopenia Induced by Imported Infectious Diseases: A Controlled Cross-Sectional Study of 17,229 Diseased German Travelers Returning from the Tropics and Subtropics.The American journal of tropical medicine and hygiene · 2016
    Article
18. Lymphocyte Perturbations in Malawian Children with Severe and Uncomplicated Malaria.Clinical and vaccine immunology : CVI · 2015
    Article
19. Plasmodium falciparum parasitaemia and malaria among pregnant women at first clinic visit in the mount Cameroon Area.BMC infectious diseases · 2015
    Article
20. Phenotypic profiling of CD8(+) T cells during Plasmodium vivax blood-stage infection.BMC infectious diseases · 2015
    Article

Corrections and comments

• Comment on
  Plasmodium falciparum induces apoptosis in human mononuclear cells.1996
• Comment on
  Rapid reemergence of T cells into peripheral circulation following treatment of severe and uncomplicated Plasmodium falciparum malaria.1997
• Comment on
  Malaria infection induces rapid elevation of the soluble Fas ligand level in serum and subsequent T lymphocytopenia: possible factors responsible for the differences in susceptibility of two species of Macaca monkeys to Plasmodium coatneyi infection.2000
• Comment on
  Cellular changes and apoptosis in the spleens and peripheral blood of mice infected with blood-stage Plasmodium chabaudi chabaudi AS.2000
• Comment on
  Increased levels of soluble Fas ligand in serum in Plasmodium falciparum malaria.2000

Authors and funding

2 authors at 1 institution in 2 countries.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as