ReviewAlcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism2000
Animal models in alcohol research.
Review in Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 2 syntheses or guidelines pooled it, 138 citations in OpenAlex.
- Modulating the endocannabinoid system in alcohol use disorder: A translational systematic review and meta-analysis of preclinical and human studies.Molecular psychiatry · 2026Pooled it
- Pooled it
- Trial
- Modeling Concurrent Hedonic Disruption During Excessive Drinking and Abstinence-Related Negative Affect in a Novel Selectively Bred Mouse Line: The Crossed High Alcohol Preferring X High Drinking in the Dark (cHAPxHDID) Mice.Alcohol, clinical & experimental research · 2026Article
- Sex and individual differences in ketamine's effects on alcohol drinking in rats.Alcohol, clinical & experimental research · 2026Article
- Alcohol-induced gut permeability defect through dysbiosis and enterocytic mitochondrial interference causing pro-inflammatory macrophages in a dose dependent manner.Scientific reports · 2025Article
- Operant ethanol self-administration behaviors do not predict sex differences in continuous access home cage drinking.Alcohol (Fayetteville, N.Y.) · 2025Article
- Review
- Understanding How Acute Alcohol Impacts Neural Encoding in the Rodent Brain.Current topics in behavioral neurosciences · 2025Review
- Tolerance and efficient metabolization of extremely high ethanol concentrations by a social wasp.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Composition of Higher Alcohols in Different Alcoholic Beverages and Their Metabolic Dynamics in Bama Pigs.Foods (Basel, Switzerland) · 2024Article
- Standard rodent diets differentially impact alcohol consumption and preference and gut microbiome diversity.bioRxiv : the preprint server for biology · 2024Article
- Standard rodent diets differentially impact alcohol consumption, preference, and gut microbiome diversity.Frontiers in neuroscience · 2024Article
- Psilocybin prevents reinstatement of alcohol seeking by disrupting the reconsolidation of alcohol-related memories.Psychopharmacology · 2023Article
- Experimental Models of Alcohol Use Disorder and Their Application for Pathophysiological Investigations.Current protocols · 2023Article
- Medications for the Treatment of Alcohol Dependence-Current State of Knowledge and Future Perspectives from a Public Health Perspective.International journal of environmental research and public health · 2023Review
- Host Factors in Dysregulation of the Gut Barrier Function during Alcohol-Associated Liver Disease.International journal of molecular sciences · 2021Review
- Reducing alcohol and/or cocaine-induced reward and toxicity via an epidermal stem cell-based gene delivery platform.Molecular psychiatry · 2021Article
- Subjective Responses to Alcohol in the Development and Maintenance of Alcohol Use Disorder.The American journal of psychiatry · 2021Article
- Andrographis paniculata and Its Main Bioactive Ingredient Andrographolide Decrease Alcohol Drinking and Seeking in Rats Through Activation of Nuclear PPARγ Pathway.Alcohol and alcoholism (Oxford, Oxfordshire) · 2021Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animal models are important tools in the study of alcohol use, abuse, and dependence because they allow researchers to use methods that cannot be used with human subjects. Animal models have been developed to study various aspects of alcohol use and dependence, including alcohol-seeking behavior, alcohol-related organ damage, tolerance to alcohol, and physical dependence on alcohol. Because animal models can be genetically manipulated, they are also valuable for research into the genetic determinants of alcoholism. Issues surrounding the use of animal models in alcohol research include the species of animal used, the method of alcohol administration, and the model's face and predictive validity.
Indexed as
Identifiers
11199281PMC6713012W1544189472What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.