ReviewDrugs & aging2000
Late onset asthma: epidemiology, diagnosis and treatment.
Review in Drugs & aging, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 50 citations in OpenAlex.
- Association of weight-adjusted-waist index with asthma prevalence and the age of first asthma onset in United States adults.Frontiers in endocrinology · 2023Article
- Asthma prevalence based on the Baidu index and China's Health Statistical Yearbook from 2011 to 2020 in China.Frontiers in public health · 2023Article
- The Role of Atopy in COPD and Asthma.Frontiers in medicine · 2021Review
- Major depressive disorder is associated with subsequent adult-onset asthma: a population-based cohort study.Epidemiology and psychiatric sciences · 2017Article
- Old dilemma: asthma with irreversible airway obstruction or COPD.Virchows Archiv : an international journal of pathology · 2015Article
- Biomarkers of progression of chronic obstructive pulmonary disease (COPD).Journal of thoracic disease · 2014Review
- The Advance of Personalized and Stratified Therapies in Bronchial Asthma: Phenotypes - Endotypes - Biomarkers.EJIFCC · 2013Article
- Interaction of occupational and personal risk factors in workforce health and safety.American journal of public health · 2012Article
- Complexities of diagnosis and treatment of allergic respiratory disease in the elderly.Drugs & aging · 2009Review
- Asthma in the elderly.Current gerontology and geriatrics research · 2009Article
- Optimal management of asthma in elderly patients: strategies to improve adherence to recommended interventions.Drugs & aging · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma is common among older persons, affecting approximately 4 to 8% of those above the age of 65 years. Despite its prevalence, late onset asthma may be misdiagnosed and inadequately treated, with important negative consequences for the patient's health. The histopathology of late onset disease appears to be similar to that of asthma in general, with persistent airway inflammation a characteristic feature. It is less clear, however, that allergic exposure and sensitisation play the same role in the development of disease in adults as they do in children. Atopy is less common among those with late onset asthma, and the prevalence of elevated immunoglobulin E levels is lower among those aged over 55 years of age than younger patients. Occupational asthma is an aetiological consideration unique to adult onset disease, with important implications for treatment. The differential diagnosis for cough, wheeze, and dyspnoea in the elderly is broad, and includes chronic obstructive bronchitis, bronchiectasis, congestive heart failure, lung cancer with endobronchial lesion and vocal cord dysfunction. Keys to accurate diagnosis include a good history and physical examination, the demonstration of reversible airways obstruction on pulmonary function tests and a favorable response to treatment. Inhaled corticosteroid therapy is recommended for patients with persistent disease, and careful instruction in the use of metered-dose inhalers is particularly important for the elderly.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.