Trial reportInternational journal of pancreatology : official journal of the International Association of Pancreatology2000
Nasogastric feeding in severe acute pancreatitis may be practical and safe.
Trial report in International journal of pancreatology : official journal of the International Association of Pancreatology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 7 syntheses or guidelines pooled it, 148 citations in OpenAlex.
- Nasogastric versus nasojejunal tube feeding for severe acute pancreatitis.The Cochrane database of systematic reviews · 2020Pooled it
- Enteral nutrition in acute pancreatitis: a review of the current evidence.World journal of gastroenterology · 2014Pooled it
- Nasogastric or nasojejunal feeding in predicted severe acute pancreatitis: a meta-analysis.Critical care (London, England) · 2013Pooled it
- Evidence-based use of enteral nutrition in acute pancreatitis.Langenbeck's archives of surgery · 2010Pooled it
- Early nasogastric enteral nutrition for severe acute pancreatitis: a systematic review.World journal of gastroenterology · 2007Pooled it
- Evidence-based treatment of acute pancreatitis: a look at established paradigms.Annals of surgery · 2006Pooled it
- Guideline
- Nasogastric or nasojejunal feeding in pediatric acute pancreatitis: a randomized controlled trial.World journal of pediatrics : WJP · 2021Trial
- Trial
- Review
- Nasogastric Nutrition versus Nasojejunal Nutrition in Patients with Severe Acute Pancreatitis: A Meta-Analysis of Randomized Controlled Trials.Gastroenterology research and practice · 2016Article
- Nutrition, inflammation, and acute pancreatitis.ISRN inflammation · 2013Review
- Endoscopist's approach to nutrition in the patient with pancreatitis.World journal of gastrointestinal endoscopy · 2012Article
- Enteral nutrition and acute pancreatitis: a review.Gastroenterology research and practice · 2011Article
- Endoscopic placement of enteral feeding tubes.World journal of gastrointestinal endoscopy · 2010Article
- The management of acute and chronic pancreatitis.Gastroenterology & hepatology · 2010Article
- Review
- Early enteral nutrition in acute pancreatitis--benefits and limitations.Langenbeck's archives of surgery · 2008Review
- Conservative approach in the management of severe acute pancreatitis: eight-year experience in a single institution.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2008Article
- Acute pancreatitis: practical considerations in nutrition support.Current gastroenterology reports · 2007Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere acute pancreatitis may be protracted and some form of nutritional support is frequently required to maintain the patient's nutritional status. Recent work has suggested that enteral feeding via a jejunal route of delivery may reduce the magnitude of the inflammatory response. Insertion of nasojejunal (NJ) tubes in the patient with severe acute pancreatitis involves both delay and inconvenience. We undertook a prospective, feasibility study to assess the safety and practicability of nasogastric (NG) feeding in patients with severe acute pancreatitis. PATIENTS AND
methodsTwenty-six patients with objective evidence of severe acute pancreatitis received nasogastric feeding within 48 h of admission to our unit.
resultsEtiology was identified as cholelithiasis (18 patients), ethanol (5), and miscellaneous (3). The median Glasgow score was 4 (range 2-7), APACHE II score 10 (4-28), and C-reactive protein concentration 286 mg/L (79-469). Fifteen patients had pancreatic and/or peripancreatic necrosis. Eleven patients developed severe organ failure, necessitating ventilatory support. Six developed multiple organ system failure, requiring inotropic support and/or renal dialysis. There were four deaths (15.3%). Nine patients underwent early, and nine late, ERCP, respectively; six necrosectomy (5 proven infected necrosis, 1 continued deterioration despite maximal support) and 4 patients internal drainage of a pseudocyst. The feed was well-tolerated in 22 patients. In 3 patients gastric stasis proved troublesome. There was no evidence of clinical or biochemical deterioration on commencing nasogastric feeding.
conclusionIt would appear that early NG feeding is usually possible in severe acute pancreatitis. In most patients it appears safe, well-tolerated, and worthy of further study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.