ArticleMolecular biology of the cell2001
The cellular level of PR500, a protein complex related to the 19S regulatory particle of the proteasome, is regulated in response to stresses in plants.
Article in Molecular biology of the cell, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 50 citations in OpenAlex.
- Protective Roles of Cytosolic and Plastidal Proteasomes on Abiotic Stress and Pathogen Invasion.Plants (Basel, Switzerland) · 2020Review
- DELLA-mediated PIF degradation contributes to coordination of light and gibberellin signalling in Arabidopsis.Nature communications · 2016Article
- Natural alleles of a proteasome α2 subunit gene contribute to thermotolerance and adaptation of African rice.Nature genetics · 2015Article
- Dynamic regulation of the COP9 signalosome in response to DNA damage.Molecular and cellular biology · 2014Article
- Proteasome regulation, plant growth and stress tolerance.Plant signaling & behavior · 2009Review
- Arabidopsis PUB22 and PUB23 are homologous U-Box E3 ubiquitin ligases that play combinatory roles in response to drought stress.The Plant cell · 2008Article
- Characterization of the VIER F-BOX PROTEINE genes from Arabidopsis reveals their importance for plant growth and development.The Plant cell · 2007Article
- Heterologous expression and molecular and cellular characterization of CaPUB1 encoding a hot pepper U-Box E3 ubiquitin ligase homolog.Plant physiology · 2006Article
- Regulated proteolysis and plant development.Plant cell reports · 2004Review
- Characterizing the stress/defense transcriptome of Arabidopsis.Genome biology · 2003Article
- Missense mutation in the PAS2 domain of phytochrome A impairs subnuclear localization and a subset of responses.The Plant cell · 2002Article
- Cytokinin growth responses in Arabidopsis involve the 26S proteasome subunit RPN12.The Plant cell · 2002Article
- Subunit interaction maps for the regulatory particle of the 26S proteasome and the COP9 signalosome.The EMBO journal · 2001Article
- Molecular characterization of subunit 6 of the COP9 signalosome and its role in multifaceted developmental processes in Arabidopsis.The Plant cell · 2001Article
- LAF1, a MYB transcription activator for phytochrome A signaling.Genes & development · 2001Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Arabidopsis seedlings and cauliflower florets, Rpn6 (a proteasome non-ATPase regulatory subunit) was found in two distinct protein complexes of approximately 800 and 500 kDa, respectively. The large complex likely represents the proteasome 19S regulator particle (RP) because it displays the expected subunit composition and all characteristics. The small complex, designated PR500, shares at least three subunits with the "lid" subcomplex of 19S RP and is loosely associated with an hsp70 protein. In Arabidopsis COP9 signalosome mutants, PR500 was specifically absent or reduced to an extent that correlates with the severity of the mutations. Furthermore, PR500 was also diminished in response to potential protein-misfolding stresses caused by the heat shock and canavanine treatment. Immunofluorescence studies suggest that PR500 has a distinct localization pattern and is enriched in specific nuclear foci. We propose that PR500 may be evolved in higher plants to cope with the frequently encountered environmental stresses.
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