ArticleMolecular biology of the cell2001
Division of mitochondria requires a novel DNM1-interacting protein, Net2p.
Article in Molecular biology of the cell, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
64 citing papers in PubMed, 161 citations in OpenAlex.
- A constricted mitochondrial morphology formed during respiration.Nature communications · 2025Article
- Isolation and Identification of Yeasts in Marcha, a Rice Wine Starter Culture From Nepal.International journal of food science · 2024Article
- Temporal control of contact site formation reveals a relationship between mitochondrial division and Num1-mediated mitochondrial tethering.Molecular biology of the cell · 2023Article
- Immunomodulatory therapy with glatiramer acetate reduces endoplasmic reticulum stress and mitochondrial dysfunction in experimental autoimmune encephalomyelitis.Scientific reports · 2023Article
- Loss of Num1-mediated cortical dynein anchoring negatively impacts respiratory growth.Journal of cell science · 2022Article
- In vitro and in vivo assays for mitochondrial fission and fusion.Methods in cell biology · 2020Article
- Mdivi-1 and mitochondrial fission: recent insights from fungal pathogens.Current genetics · 2019Review
- Regulation of Mitochondrial Dynamics by Proteolytic Processing and Protein Turnover.Antioxidants (Basel, Switzerland) · 2018Review
- Recent insights into the structure and function of Mitofusins in mitochondrial fusion.F1000Research · 2018Review
- Connecting mitochondrial dynamics and life-or-death events via Bcl-2 family proteins.Neurochemistry international · 2017Review
- A Targeted Mutation Identified through pKa Measurements Indicates a Postrecruitment Role for Fis1 in Yeast Mitochondrial Fission.The Journal of biological chemistry · 2016Article
- Dynamin-Related Protein 1 Deficiency Improves Mitochondrial Fitness and Protects against Progression of Diabetic Nephropathy.Journal of the American Society of Nephrology : JASN · 2016Article
- Multiple faces of dynamin-related protein 1 and its role in Alzheimer's disease pathogenesis.Biochimica et biophysica acta · 2016Review
- Article
- Mitochondrial division and fusion in metabolism.Current opinion in cell biology · 2015Review
- Biosynthesis and roles of phospholipids in mitochondrial fusion, division and mitophagy.Cellular and molecular life sciences : CMLS · 2014Review
- The dual role of cyclin C connects stress regulated gene expression to mitochondrial dynamics.Microbial cell (Graz, Austria) · 2014Review
- Shaping the dynamic mitochondrial network.BMC biology · 2014Review
- Dynamin assembly strategies and adaptor proteins in mitochondrial fission.Current biology : CB · 2013Review
- Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Mitochondria are dynamic organelles that undergo frequent division and fusion, but the molecular mechanisms of these two events are not well understood. Dnm1p, a mitochondria-associated, dynamin-related GTPase was previously shown to mediate mitochondrial fission. Recently, a genome-wide yeast two-hybrid screen identified an uncharacterized protein that interacts with Dnm1p. Cells disrupted in this new gene, which we call NET2, contain a single mitochondrion that consists of a network formed by interconnected tubules, similar to the phenotype of dnm1 Delta cells. NET2 encodes a mitochondria-associated protein with a predicted coiled-coil region and six WD-40 repeats. Immunofluorescence microscopy indicates that Net2p is located in distinct, dot-like structures along the mitochondrial surface, many of which colocalize with the Dnm1 protein. Fluorescence and immunoelectron microscopy shows that Dnm1p and Net2p preferentially colocalize at constriction sites along mitochondrial tubules. Our results suggest that Net2p is a new component of the mitochondrial division machinery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.