ArticleInfection and immunity2001
Mycobacterium avium invades the intestinal mucosa primarily by interacting with enterocytes.
Article in Infection and immunity, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Article
- TheMicroorganisms · 2025Review
- Mapping Crohn's Disease Pathogenesis with Mycobacterium paratuberculosis: A Hijacking by a Stealth Pathogen.Digestive diseases and sciences · 2024Review
- Diminishing of Helicobacter pylori adhesion to Cavia porcellus gastric epithelial cells by BCG vaccine mycobacteria.Scientific reports · 2023Article
- Disseminated MAI in an HIV Patient-An Unusual Presentation.Medicines (Basel, Switzerland) · 2023Article
- Metabolic pathways that permitFrontiers in cellular and infection microbiology · 2023Article
- Article
- Review
- Disseminated Mycobacterium avium Infection Presenting with Bladder Lesions in a Patient with Interferon-γ-neutralizing Autoantibodies.Internal medicine (Tokyo, Japan) · 2018Article
- Establishing Caenorhabditis elegans as a model for Mycobacterium avium subspecies hominissuis infection and intestinal colonization.Biology open · 2015Article
- MR1-restricted mucosal associated invariant T (MAIT) cells in the immune response to Mycobacterium tuberculosis.Immunological reviews · 2015Review
- Host response to nontuberculous mycobacterial infections of current clinical importance.Infection and immunity · 2014Article
- Non-tuberculous mycobacteria have diverse effects on BCG efficacy against Mycobacterium tuberculosis.Tuberculosis (Edinburgh, Scotland) · 2014Article
- Mycobacterium avium biofilm attenuates mononuclear phagocyte function by triggering hyperstimulation and apoptosis during early infection.Infection and immunity · 2014Article
- No holes barred: invasion of the intestinal mucosa by Mycobacterium avium subsp. paratuberculosis.Infection and immunity · 2013Review
- Article
- Peyer's Patches: The Immune Sensors of the Intestine.International journal of inflammation · 2010Article
- Peyer's patch-deficient mice demonstrate that Mycobacterium avium subsp. paratuberculosis translocates across the mucosal barrier via both M cells and enterocytes but has inefficient dissemination.Infection and immunity · 2010Article
- Capture of heat-killed Mycobacterium bovis bacillus Calmette-Guérin by intelectin-1 deposited on cell surfaces.Glycobiology · 2009Article
- Invasion and persistence of Mycobacterium avium subsp. paratuberculosis during early stages of Johne's disease in calves.Infection and immunity · 2007Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Previous studies have demonstrated that Mycobacterium avium can invade intestinal epithelial cells both in vitro and in vivo. When given to mice orally, M. avium preferentially interacts with the intestinal mucosa at the terminal ileum. We evaluated the mechanism(s) of M. avium binding and invasion of the intestinal mucosa using three different systems: (i) electron microscopy following administration of M. avium into an intestinal loop in mice, (ii) quantitative comparison of the bacterial load in Peyer's patch areas of the terminal ileum versus areas that do not contain Peyer's patches, and (iii) investigation of the ability of M. avium to cause disseminated infection following oral administration using B-cell-deficient mice, lacking Peyer's patches, in comparison with C57BL/6 black mice. By all approaches, M. avium was found to invade the intestinal mucosa by interacting primarily with enterocytes and not with M cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.