ArticleArthritis research2001
Role of IL-12 in Staphylococcus aureus-triggered arthritis and sepsis.
Article in Arthritis research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 46 citations in OpenAlex.
- Exploring the role of bacterial virulence factors and host elements in septic arthritis: insights from animal models for innovative therapies.Frontiers in microbiology · 2024Review
- Bacteria and Host Interplay inPathogens (Basel, Switzerland) · 2021Review
- Article
- Role of Leptin in Inflammation and Vice Versa.International journal of molecular sciences · 2020Review
- Neutrophils: Beneficial and Harmful Cells in Septic Arthritis.International journal of molecular sciences · 2018Review
- Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis.Nature communications · 2016Article
- Article
- Azithromycin in combination with riboflavin decreases the severity of Staphylococcus aureus infection induced septic arthritis by modulating the production of free radicals and endogenous cytokines.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2013Article
- Effects of small intestinal submucosa (SIS) on the murine innate immune microenvironment induced by heat-killed Staphylococcus aureus.PloS one · 2012Article
- Possible protective role of chloramphenicol in TSST-1 and coagulase-positive Staphylococcus aureus-induced septic arthritis with altered levels of inflammatory mediators.Inflammation · 2011Article
- Role of fibronectin-binding proteins A and B in in vitro cellular infections and in vivo septic infections by Staphylococcus aureus.Infection and immunity · 2011Article
- Pathogenic role of macrophages in intradermal infection of methicillin-resistant Staphylococcus aureus in thermally injured mice.Infection and immunity · 2010Article
- Interleukin 12 a key immunoregulatory cytokine in infection applications.International journal of molecular sciences · 2010Review
- Recognition of Staphylococcus aureus by the innate immune system.Clinical microbiology reviews · 2005Review
- Intranasal immunization with recombinant Lactococcus lactis secreting murine interleukin-12 enhances antigen-specific Th1 cytokine production.Infection and immunity · 2003Article
- Interleukin-10 ameliorates the outcome of Staphylococcus aureus arthritis by promoting bacterial clearance.Clinical and experimental immunology · 2002Article
- Combined antibiotic and free radical trap treatment is effective at combating Staphylococcus-aureus-induced septic arthritis.Arthritis research · 2002Article
- Leptin in septic arthritis: decreased levels during infection and amelioration of disease activity upon its administration.Arthritis research · 2001Article
- Synovial cytokine mRNA expression during arthritis triggered by CpG motifs of bacterial DNA.Arthritis research · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study demonstrates that endogenous production of IL-12 is crucial for survival in Staphylococcus aureus-induced arthritis in mice. Staphylococcal load is enhanced in several organs, because of lack of IL-12. This might be due to decreased production of IFN-gamma in IL-12-deficient mice. Although IL-12-deficient mice were exposed to higher staphylococcal load, they demonstrated no increased severity of arthritis as compared with control animals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.