ReviewArthritis research2001
The human exosome: an autoantigenic complex of exoribonucleases in myositis and scleroderma.
Review in Arthritis research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 75 citations in OpenAlex.
- Review
- Prevalence of Small A-Delta Fiber Neuropathy in Sjögren's Disease: Findings from a Cohort Study.International journal of molecular sciences · 2025Article
- Polyadenylated versions of small non-coding RNAs inMicrobial cell (Graz, Austria) · 2024Article
- The axis of complement C1 and nucleolus in antinuclear autoimmunity.Frontiers in immunology · 2023Review
- Article
- Molecular characteristics and functional differences of anti-PM/Scl autoantibodies and two other distinct and unique supramolecular structures known as "EXOSOMES".Autoimmunity reviews · 2020Review
- Muscular and extramuscular clinical features of patients with anti-PM/Scl autoantibodies.Neurology · 2018Article
- Exosomes as a novel pathway for regulating development and diseases of the skin.Biomedical reports · 2018Article
- Exosome analysis: a promising biomarker system with special attention to saliva.The Journal of membrane biology · 2014Review
- The exozyme model: a continuum of functionally distinct complexes.RNA (New York, N.Y.) · 2011Review
- Dis3-like 1: a novel exoribonuclease associated with the human exosome.The EMBO journal · 2010Article
- Characterization of Saccharomyces cerevisiae Npa2p (Urb2p) reveals a low-molecular-mass complex containing Dbp6p, Npa1p (Urb1p), Nop8p, and Rsa3p involved in early steps of 60S ribosomal subunit biogenesis.Molecular and cellular biology · 2007Article
- Sequence-specific RNA binding mediated by the RNase PH domain of components of the exosome.RNA (New York, N.Y.) · 2006Article
- Alternative splicing factor ASF/SF2 is down regulated in inflamed muscle.Journal of clinical pathology · 2006Article
- Clinical evaluation of autoantibodies to a novel PM/Scl peptide antigen.Arthritis research & therapy · 2005Article
- Organization of the MASP2 locus and its expression profile in mouse and rat.Mammalian genome : official journal of the International Mammalian Genome Society · 2004Article
- Antibodies in scleroderma: direct pathogenicity and phenotypic associations.Current rheumatology reports · 2004Review
- Identification and cloning of human polynucleotide phosphorylase, hPNPase old-35, in the context of terminal differentiation and cellular senescence.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Idiopathic inflammatory myopathy: autoantibody update.Current rheumatology reports · 2002Review
- CML28 is a broadly immunogenic antigen, which is overexpressed in tumor cells.Cancer research · 2002Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The anti-PM/Scl autoantibodies are known to characterize a subset of autoimmune patients with myositis, scleroderma (Scl), and the PM/Scl overlap syndrome. The major autoantigens that are recognized by anti-PM/Scl autoantibodies are designated PM/Scl-100 and PM/Scl-75. These autoantigens have been reported to associate into a large complex consisting of 11 to 16 proteins and to play a role in ribosome synthesis. Recently, it was discovered that the PM/Scl complex is the human counterpart of the yeast (Saccharomyces cerevisiae) exosome, which is an RNA-processing complex consisting of 11 3' --> 5' exoribonucleases. To date, 10 human exosome components have been identified, although only some of these were studied in more detail. In this review, we discuss some recent advances in the characterization of the PM/Scl complex.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.