Evidence map›Paper›PMID 11177771›Full record

ReviewCurrent rheumatology reports2001

Update on synovitis.

Z Szekanecz, A E Koch

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Current rheumatology reports, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice.Proceedings of the National Academy of Sciences of the United States of America · 2002
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Z SzekaneczDepartment of Medicine, Division of Arthritis and Connective Tissue Diseases, Northwestern University Medical School, Ward Building 3-315, 303 East Chicago Avenue, Chicago, IL 60611, USA.
A E Koch
Northwestern University · US

Funding

SUPERANTIGEN INTERACTIONS WITH MHC CLASS II ANTIGENSP60AR030692 · NIAMS · NORTHWESTERN UNIVERSITY · PI CHANG, ROWLAND W · 1986 to 2001
$2.1M
CHEMOTACTIC CYTOKINES IN RHEUMATOID ARTHRITISR29AR041492 · NIAMS · NORTHWESTERN UNIVERSITY · PI KOCH, ALISA E · 1992 to 1996
–
NIAMS NIH HHS AR-30692NIAMS NIH HHS AR-40987NIAMS NIH HHS AR-41492
6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is an inflammatory disorder associated with chronic synovitis, eventually leading to cartilage and bone destruction in the joints. Synovitis is associated with the activation of various cells in the synovium including synovial lining cells, interstitial macrophages, endothelial cells, lymphocytes, and fibroblasts. The key mechanisms underlying synovitis include inflammatory cell adhesion and activation, the production of mediators (such as cytokines, chemokines, and growth factors), angiogenesis, joint destruction, fibrosis, and bone resorption. These important events, as well as the role of inflammatory cells, cell surface molecules, and soluble mediators are updated and discussed in this review. Some aspects and strategies of current or future immunotherapy are also discussed because these animal and human trials provide information on the pathogenesis of inflammatory synovitis.

Indexed as

AnimalsBone and BonesCell AdhesionCell CommunicationCell MovementCytokinesHumansImmunotherapyInflammation MediatorsJointsNeovascularization, PhysiologicSynovial MembraneSynovitisCytokinesInflammation Mediators

Identifiers

PMID11177771
OpenAlexW1993040702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.