ReviewOncogene2000
The Ets-transcription factor family in embryonic development: lessons from the amphibian and bird.
Review in Oncogene, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 47 citations in OpenAlex.
- ERG-deficient endothelium identifies IL-8/CXCR2 axis as a therapeutic target for resolving neutrophilic lung vascular injury.JCI insight · 2026Article
- Elf3 deficiency during zebrafish development alters extracellular matrix organization and disrupts tissue morphogenesis.PloS one · 2022Article
- Multi-omics analyses of early liver injury reveals cell-type-specific transcriptional and epigenomic shift.BMC genomics · 2021Article
- Reprogramming normal human epithelial tissues to a common, lethal neuroendocrine cancer lineage.Science (New York, N.Y.) · 2018Article
- Exploratory bioinformatics investigation reveals importance of "junk" DNA in early embryo development.BMC genomics · 2017Article
- An in vivo screen to identify candidate neurogenic genes in the developing Xenopus visual system.Developmental biology · 2015Article
- Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages.Developmental biology · 2014Article
- The ETS transcription factor Etv1 mediates FGF signaling to initiate proneural gene expression during Xenopus laevis retinal development.Mechanisms of development · 2014Article
- Effective induction of cells expressing GABAergic neuronal markers from mouse embryonic stem cell.In vitro cellular & developmental biology. Animal · 2013Article
- Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis.Development (Cambridge, England) · 2012Article
- Sonic Hedgehog-signalling patterns the developing chicken comb as revealed by exploration of the pea-comb mutation.PloS one · 2012Article
- Deletion of ETS-1, a gene in the Jacobsen syndrome critical region, causes ventricular septal defects and abnormal ventricular morphology in mice.Human molecular genetics · 2010Article
- Evolution of adaptive immune recognition in jawless vertebrates.Seminars in immunology · 2010Review
- A mouse embryonic stem cell bank for inducible overexpression of human chromosome 21 genes.Genome biology · 2010Article
- Antiinflammatory effects of the ETS factor ERG in endothelial cells are mediated through transcriptional repression of the interleukin-8 gene.Circulation research · 2009Article
- A Myc-Slug (Snail2)/Twist regulatory circuit directs vascular development.Development (Cambridge, England) · 2008Article
- Ets-1 regulates radial glia formation during vertebrate embryogenesis.Organogenesis · 2007Article
- Thymomegaly, microsplenia, and defective homeostatic proliferation of peripheral lymphocytes in p51-Ets1 isoform-specific null mice.Molecular and cellular biology · 2007Article
- Combinatorial function of ETS transcription factors in the developing vasculature.Developmental biology · 2007Article
- Structure and function of ETAA16: a novel cell surface antigen in Ewing's tumours.Cancer immunology, immunotherapy : CII · 2006Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This chapter reviews the expression and role of Ets-genes during embryogenesis of amphibians and birds. In addition to overlapping expression domains, some of them exhibit cell type-specific expression. Many of them are expressed in migratory cells: neural crest, endothelial, and pronephric duct cells for instance. They are also transcribed in embryonic areas affected by epithelio-mesenchymal transitions. Both processes involve modifications of cellular adhesion. Ets-family genes appear to coordinate changes in the expression of adhesion molecules and degradation of the extracellular matrix upon regulation of matrix metalloproteinases and their specific inhibitors. These functions are essential for physiological processes like tissue remodelling during embryogenesis or wound healing. Unfortunately they also play a harmful role in metastasis. Recent studies in the nervous system showed that Ets-genes contribute to the establishment of a cellular identity. This identity could rely on definite cell-surface determinants, among which cadherins could play an important role. In addition to cell-type specific expression, other factors contribute to the specificity of function of Ets-genes. These genes have a broad specificity of recognition of target sequences in gene promoters, insufficient for accurate control of gene expression. A fine tuning could arise from combinatorial interactions with other Ets- or accessory proteins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.