ReviewOncogene2000
Genetic analysis of ETS genes in C. elegans.
Review in Oncogene, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- microRNAs: Critical Players during Helminth Infections.Microorganisms · 2022Review
- Identifying the Caenorhabditis elegans vulval transcriptome.G3 (Bethesda, Md.) · 2022Article
- The Signaling Network Controlling C. elegans Vulval Cell Fate Patterning.Journal of developmental biology · 2018Review
- Article
- The ETS-5 transcription factor regulates activity states inProceedings of the National Academy of Sciences of the United States of America · 2017Article
- Axon Regeneration Is Regulated by Ets-C/EBP Transcription Complexes Generated by Activation of the cAMP/Ca2+ Signaling Pathways.PLoS genetics · 2015Article
- ERG transcriptional networks in primary acute leukemia cells implicate a role for ERG in deregulated kinase signaling.PloS one · 2013Article
- The Capicua repressor--a general sensor of RTK signaling in development and disease.Journal of cell science · 2012Review
- Differentiation of carbon dioxide-sensing neurons in Caenorhabditis elegans requires the ETS-5 transcription factor.Genetics · 2011Article
- Genomic and biochemical insights into the specificity of ETS transcription factors.Annual review of biochemistry · 2011Review
- ETS-4 is a transcriptional regulator of life span in Caenorhabditis elegans.PLoS genetics · 2010Article
- The ETS transcription factor GABPalpha is essential for early embryogenesis.Molecular and cellular biology · 2004Article
- Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors.Nucleic acids research · 2004Article
- The biology of the Ets1 proto-oncogene.Molecular cancer · 2003Review
- Sp100 interacts with ETS-1 and stimulates its transcriptional activity.Molecular and cellular biology · 2002Article
- An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors.Genes & development · 2002Article
- Highly conserved amino acids in Pax and Ets proteins are required for DNA binding and ternary complex assembly.Nucleic acids research · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recent completion of the Caenorhabditis elegans genome has revealed that this nematode worm has 10 members of the ETS gene family. Isolation and analysis of C. elegans mutants and subsequent screens to identify interacting genes can proceed very quickly in this model organism. Molecular genetic analysis of the receptor tyrosine kinase-Ras-MAP kinase signaling pathway in C. elegans identified the ETS family transcription factor Lin-1 as a nuclear effector of this evolutionarily conserved signal transduction pathway. Here we review classical genetic approaches used to discover the role of Lin-1 in the Ras-MAP kinase signaling pathway and describe new technologies that can be applied to the analyses of signaling pathways and transcription factor regulatory networks in C. elegans.
Indexed as
Identifiers
11175356What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.