ArticlePathology oncology research : POR1996
Apoptosis: A Current Molecular Analysis.
Article in Pathology oncology research : POR, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
12 citing papers in PubMed, 52 citations in OpenAlex.
- Construction and validation of a novel apoptosis-associated prognostic signature related to osteosarcoma metastasis and immune infiltration.Translational oncology · 2022Article
- Development and validation of apoptosis-related signature and molecular subtype to improve prognosis prediction in osteosarcoma patients.Journal of clinical laboratory analysis · 2022Article
- A Novel Apoptosis-Related Gene Signature Predicts Biochemical Recurrence of Localized Prostate Cancer After Radical Prostatectomy.Frontiers in genetics · 2020Article
- Role of Bax/Bcl-2 family members in green tea polyphenol induced necroptosis of p53-deficient Hep3B cells.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Article
- The involvement of secondary neuronal damage in the development of neuropsychiatric disorders following brain insults.Frontiers in neurology · 2014Review
- Toxicological aspects of the use of phenolic compounds in disease prevention.Interdisciplinary toxicology · 2011Article
- Apoptotic factors (Bcl-2 and Bax) and diabetic retinopathy in type 2 diabetes.Journal of molecular histology · 2010Article
- Comparative proteomic analysis of malformed umbilical cords from somatic cell nuclear transfer-derived piglets: implications for early postnatal death.BMC genomics · 2009Article
- DBCCR1 mediates death in cultured bladder tumor cells.Oncogene · 2004Article
- CD4+ and CD19+ splenocytes undergo apoptosis during an experimental murine infection with Taenia crassiceps.Parasitology research · 2003Article
- Apoptosis-related proteins, BCL-2, BAX, FAS, FAS-L and PCNA in liver biopsies of patients with chronic hepatitis B virus infection.Pathology oncology research : POR · 2000Article
- Modulation of antioxidant enzymes and apoptosis in mice by dietary lipids and treadmill exercise.Journal of clinical immunology · 1999Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Apoptosis is a cell suicide program characterized by distinct morphological (cell shrinkage, membrane blebbing, pyknosis, chromatin margination, denser cytoplasmic images) and biochemical (e.g., DNA fragmentation into distinct ladders; degradation of apoptotic markers such as PARP and nuclear lamins) features. It is involved in multiple physiological processes examplified by involution of mammary tissues, embryonic development, homeostatic maintenance of tissues and organs, and maturation of the immune system, as well as in many pathological conditions represented by neurologic degeneration (Alzeimer's disease), autoimmune and inflammatory diseases, etiology of atherosclerosis, AIDS, and oncogenesis and tumor progression. Numerous molecular entities have been shown to regulate the apoptotic process. This review provides a concise summary of the recent data on the role of oncogenes/tumor suppressor genes, cytokines and growth factors/growth factor receptors, intracellular signal transducers, cell cycle regulators, reactive oxygen species or other free radicals, extracellular matrix regulators/cell adhesion molecules, and specific endonucleases and cytoplasmic proteases (the ICE family proteins) in regulating cell survival and apoptosis. Elucidation of the molecular mechanisms regulating apoptosis bears tremendous impact on enhancing our understanding of many diseases inflicting the human beings and undoubtedly brings us hope for the cure of these diseases.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.