ArticleBritish journal of cancer2001
Season of birth and diagnosis of children with leukaemia: an analysis of over 15 000 UK cases occurring from 1953-95.
Article in British journal of cancer, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Does month of birth influence colorectal cancer prognosis?Langenbeck's archives of surgery · 2023Observational
- Seasonal trends of diagnosis of childhood malignant diseases and viral prevalence in South Korea.Cancer epidemiology · 2017Article
- Is Month of Birth a Risk Factor for Colorectal Cancer?Gastroenterology research and practice · 2017Article
- Perinatal risk factors for acute myeloid leukemia.European journal of epidemiology · 2015Article
- Perinatal and familial risk factors for acute lymphoblastic leukemia in a Swedish national cohort.Cancer · 2015Article
- First description of seasonality of birth and diagnosis amongst teenagers and young adults with cancer aged 15-24 years in England, 1996-2005.BMC cancer · 2013Article
- Evaluation of seasonality in the diagnosis of acute myeloid leukaemia among adults in the United States, 1992-2008.British journal of haematology · 2013Article
- The relationship between seasonal variation in the diagnosis of acute lymphoblastic leukemia and its prognosis in children.Turkish journal of haematology : official journal of Turkish Society of Haematology · 2012Article
- Seasonal variation of childhood acute lymphoblastic leukaemia is different between girls and boys.Pathology oncology research : POR · 2008Article
- A method to model season of birth as a surrogate environmental risk factor for disease.International journal of environmental research and public health · 2008Article
- Risk factors for acute leukemia in children: a review.Environmental health perspectives · 2007Review
- Evidence of seasonality in the diagnosis of monocytic leukaemia.British journal of cancer · 2002Article
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4 authors.
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Abstract
If infections are involved in the aetiology of childhood leukaemia then seasonal variation in the birth or onset dates of the malignancy may be apparent. Previous studies that have examined seasonality of these dates have produced conflicting results. Using population-based data from the National Registry of Childhood Tumours we conducted a larger study than any to date of 15 835 cases of childhood leukaemia born and diagnosed in the UK between 1953-95. We found no evidence of seasonality in either month of birth or month of diagnosis overall or in any subgroups by age, sex, histology or immunophenotype. We did however find a significant (P = 0.01) February peak in month of birth for cases born before 1960 and a significant (P = 0.02) August peak in month of diagnosis for those diagnosed before 1962. Whilst these findings may be due to chance they are also consistent with changes over time in the seasonality of exposure, or immunological response, to a relevant infection. Changes in the seasonal variation in the fatality rate of a pre-leukaemic illness, such as pneumonia, could be another explanation.
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