ArticlePlant physiology2001
Sugar coordinately and differentially regulates growth- and stress-related gene expression via a complex signal transduction network and multiple control mechanisms.
Article in Plant physiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
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Who cites it
58 citing papers in PubMed, 172 citations in OpenAlex.
- Integrated morpho-physiological, metabolomic and transcriptomic profiling uncovers ethylene-mediated metabolic regulation shaping drought resilience in wheat.BMC plant biology · 2026Article
- The optimization of crop response to climatic stress through modulation of plant stress response mechanisms. Opportunities for biostimulants and plant hormones to meet climate challenges.The New phytologist · 2026Review
- Impact of Soil Drought on Yield and Leaf Sugar Content in Wheat: Genotypic and Phenotypic Relationships Compared Using a Doubled Haploid Population.International journal of molecular sciences · 2025Article
- Transcriptional corepressor OsTPR1 regulates tillering and lateral root development in rice.Scientific reports · 2025Article
- Effect of drought acclimation on sugar metabolism in millet.Protoplasma · 2025Article
- Sugar delivery at the tomato root and root galls after Meloidogyne incognita infestation.BMC plant biology · 2024Article
- Histochemical, metabolic and ultrastructural changes in leaf patelliform nectaries explain extrafloral nectar synthesis and secretion in Clerodendrum chinense.Annals of botany · 2024Article
- Sucrose treatment delays senescence and maintains the postharvest quality of baby mustard (Food chemistry: X · 2022Article
- Transcriptome analysis provides new ideas for studying the regulation of glucose-induced lignin biosynthesis in pear calli.BMC plant biology · 2022Article
- Metabolomics Analysis Provides New Insights Into the Molecular Mechanisms of Parasitic Plant Dodder ElongationFrontiers in plant science · 2022Article
- Carbon Starved Anther modulates sugar and ABA metabolism to protect rice seed germination and seedling fitness.Plant physiology · 2021Article
- Population Evolution, Genetic Diversity and Structure of the Medicinal Legume,Frontiers in plant science · 2021Article
- Differential responses of photosynthetic parameters and its influence on carbohydrate metabolism in some contrasting rice (Oryza sativa L.) genotypes under arsenate stress.Ecotoxicology (London, England) · 2020Article
- Comparative Transcriptome, Metabolome, and Ionome Analysis of Two Contrasting Common Bean Genotypes in Saline Conditions.Frontiers in plant science · 2020Article
- Sugar Signaling and Post-transcriptional Regulation in Plants: An Overlooked or an Emerging Topic?Frontiers in plant science · 2020Review
- Article
- Metabolic response to drought in six winter wheat genotypes.PloS one · 2019Article
- Effect of glucose on the morpho-physiology, photosynthetic efficiency, antioxidant system, and carbohydrate metabolism in Brassica juncea.Protoplasma · 2019Article
- Article
- The Sugar-Signaling Hub: Overview of Regulators and Interaction with the Hormonal and Metabolic Network.International journal of molecular sciences · 2018Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In plants, sugars are required to sustain growth and regulate gene expression. A large set of genes are either up- or down-regulated by sugars; however, whether there is a common mechanism and signal transduction pathway for differential and coordinated sugar regulation remain unclear. In the present study, the rice (Oryza sativa cv Tainan 5) cell culture was used as a model system to address this question. Sucrose and glucose both played dual functions in gene regulation as exemplified by the up-regulation of growth-related genes and down-regulation of stress-related genes. Sugar coordinately but differentially activated or repressed gene expression, and nuclear run-on transcription and mRNA half-life analyses revealed regulation of both the transcription rate and mRNA stability. Although coordinately regulated by sugars, these growth- and stress-related genes were up-regulated or down-regulated through hexokinase-dependent and/or hexokinase-independent pathways. We also found that the sugar signal transduction pathway may overlap the glycolytic pathway for gene repression. alpha-Amylase and the stress-related genes identified in this study were coordinately expressed under sugar starvation, suggesting a convergence of the nutritional and environmental stress signal transduction pathways. Together, our studies provide a new insight into the complex signal transduction network and mechanisms of sugar regulation of growth and stress-related genes in plants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.