Mother-to-infant transmission of HIV-1: the placenta fights back.

S A Spector

Abstract read

In one paragraph

Article in The Journal of clinical investigation, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

Immunology of pediatric HIV infection.Immunological reviews · 2013
Review
The role of co-infections in mother-to-child transmission of HIV.Current HIV research · 2013
Review
Host genetic determinants of human immunodeficiency virus infection and disease progression in children.Pediatric research · 2009
Review

4 · The record

Corrections and comments

Commented on by
Leukemia inhibitory factor inhibits HIV-1 replication and is upregulated in placentae from nontransmitting women.2001

5 · Who and what money

Authors and funding

1 author.

S A SpectorDepartment of Pediatrics, Division of Infectious Diseases, University of California-San Diego, Stein Clinical Research Building, 9500 Gilman Drive, La Jolla, California 92093-0672, USA. saspector@ucsd.edu

Funding

VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Maile Ann Young Karris · 1994 to 2026

$78.4M

PEDIATRIC AIDS CLINICAL TRIALS GROUPU01AI027563 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SPECTOR, STEPHEN A · 1988 to 2006

$6.4M

PEDIATRIC AIDS--FACTORS IN TRANSMISSION AND PATHOLOGYR01AI039004 · NIAID · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI SPECTOR, STEPHEN A · 1995 to 2005

$1.5M

NIAID NIH HHS AI-27563NIAID NIH HHS AI-36214NIAID NIH HHS AI-39004NIAID NIH HHS P30 AI036214NIAID NIH HHS R01 AI039004NIAID NIH HHS U01 AI027563

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HIV-1Infectious Disease Transmission, VerticalAdultAnti-HIV AgentsFemaleGene Expression RegulationHIV InfectionsHumansInfant, NewbornPlacentaPregnancyReceptors, CCR5Receptors, CXCR4Virus ReplicationAnti-HIV AgentsReceptors, CCR5Receptors, CXCR4

Identifiers

PMID11160148

DOI10.1172/JCI12094

PMCPMC199204

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.