Evidence map›Paper›PMID 11160119›Full record

ArticleJournal of bacteriology2001

TFE, an archaeal transcription factor in Methanobacterium thermoautotrophicum related to eucaryal transcription factor TFIIEalpha.

B L Hanzelka, T J Darcy, J N Reeve

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The cutting edge of archaeal transcription.Emerging topics in life sciences · 2018
    Article
  6. Article
  7. Transcription Regulation in Archaea.Journal of bacteriology · 2016
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

B L HanzelkaDepartment of Microbiology, The Ohio State University, Columbus, Ohio 43210, USA.
T J Darcy
J N Reeve
The Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the archaeon Methanobacterium thermoautotrophicum, MTH1669 encodes a protein with a sequence related to the N-terminal sequences of the alpha-subunits of eucaryal general transcription factor TFIIE. The recombinant MTH1669 gene product has been purified and shown to stimulate transcription in vitro from M. thermoautotrophicum promoters that were almost inactive or much less active in reaction mixtures that contained only M. thermoautotrophicum RNA polymerase, TATA-binding protein and transcription factor B. As all complete archaeal genome sequences contain an MTH1669 homolog, the protein encoded by this gene is apparently the first characterized example of a transcription activator, here designated TFE, that may be universally present in the Archaea.

Indexed as

Transcription Factors, TFIIAmino Acid SequenceArchaeal ProteinsBacterial ProteinsCloning, MolecularDNA-Binding ProteinsGene Expression Regulation, ArchaealHumansHydrogenaseMethaneMethanobacteriumMolecular Sequence DataMutagenesisRecombinant ProteinsSequence Homology, Amino AcidTemplates, GeneticArchaeal ProteinsBacterial ProteinsDNA-Binding ProteinsHmtB protein, Methanothermobacter thermautotrophicusHydrogenaseMethaneRecombinant ProteinsTranscription FactorsTranscription Factors, TFIItranscription factor TFIIE

Identifiers

PMID11160119
PMCPMC95073
OpenAlexW2154379317

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.