Evidence map›Paper›PMID 11160115›Full record

ArticleJournal of bacteriology2001

The miaA mutator phenotype of Escherichia coli K-12 requires recombination functions.

J Zhao, H E Leung, M E Winkler

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

J ZhaoDepartment of Microbiology and Molecular Genetics, University of Texas-Houston Medical School, Houston, Texas 77030, USA.
H E Leung
M E Winkler
The University of Texas Health Science Center at Houston · US

Funding

REGULATION OF MISMATCH REPAIR IN A MODEL E COLI SYSTEMR01CA077193 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI DOMBROSKI, ALICIA J. · 1998 to 2001
$454k
NCI NIH HHS R01-CA77193
6 · The paper itself

Abstract

miaA mutants, which contain A-37 instead of the ms(2)i(6)A-37 hypermodification in their tRNA, show a moderate mutator phenotype leading to increased GC-->TA transversion. We show that the miaA mutator phenotype is dependent on recombination functions similar to, but not exactly the same as, those required for translation stress-induced mutagenesis.

Indexed as

Adenosine TriphosphatasesDNA-Binding ProteinsEscherichia coli ProteinsMutationRecombination, GeneticAlkyl and Aryl TransferasesBacterial ProteinsBase Pair MismatchDNA RepairEscherichia coliMutS DNA Mismatch-Binding ProteinPhenotypeRNA, Transfer, HisSulfurtransferasesAdenosine Triphosphatasesadenylate isopentenyltransferaseAlkyl and Aryl TransferasesBacterial ProteinsDNA-Binding ProteinsEscherichia coli Proteinsisopentenyl-adenosine i6a thiotransferaseMiaB protein, E coliMutS DNA Mismatch-Binding ProteinMutS protein, E coliRNA, Transfer, HisSulfurtransferases

Identifiers

PMID11160115
PMCPMC95069
OpenAlexW2130447654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.