ArticleJournal of bacteriology2001
Identification and characterization of gsp65, an organic hydroperoxide resistance (ohr) gene encoding a general stress protein in Enterococcus faecalis.
Article in Journal of bacteriology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 54 citations in OpenAlex.
- Linking oxidative stress defense to biofilm architecture: Ohr mediates strain-dependent persistence inVirulence · 2026Article
- Antimicrobial Biocides Susceptibility and Tolerance-Associated Genes in Enterococcus faecalis and Enterococcus faecium Isolates Collected from Human and Environmental Sources.Current microbiology · 2022Article
- Organic Hydroperoxide Resistance GeneApplied and environmental microbiology · 2021Article
- TheJournal of bacteriology · 2019Article
- Adaptation to Adversity: the Intermingling of Stress Tolerance and Pathogenesis in Enterococci.Microbiology and molecular biology reviews : MMBR · 2019Review
- Mechanisms of Bacterial Tolerance and Persistence in the Gastrointestinal and Respiratory Environments.Clinical microbiology reviews · 2018Review
- Metagenomics of pigmented and cholesterol gallstones: the putative role of bacteria.Scientific reports · 2018Article
- Transcriptomic response of Enterococcus faecalis V583 to low hydrogen peroxide levels.Current microbiology · 2015Article
- Transcriptome analysis of Enterococcus faecalis in response to alkaline stress.Frontiers in microbiology · 2015Article
- The Intraperitoneal Transcriptome of the Opportunistic Pathogen Enterococcus faecalis in Mice.PloS one · 2015Article
- Inactivation of the organic hydroperoxide stress resistance regulator OhrR enhances resistance to oxidative stress and isoniazid in Mycobacterium smegmatis.Journal of bacteriology · 2015Article
- Functional characterization of osmotically inducible protein C (MG_427) from Mycoplasma genitalium.Journal of bacteriology · 2014Article
- The Spx regulator modulates stress responses and virulence in Enterococcus faecalis.Infection and immunity · 2012Article
- Macrophage replication screen identifies a novel Francisella hydroperoxide resistance protein involved in virulence.PloS one · 2011Article
- Article
- The transcriptome of the nosocomial pathogen Enterococcus faecalis V583 reveals adaptive responses to growth in blood.PloS one · 2009Article
- The Mycoplasma genitalium MG_454 gene product resists killing by organic hydroperoxides.Journal of bacteriology · 2009Article
- Mutational analysis of active site residues essential for sensing of organic hydroperoxides by Bacillus subtilis OhrR.Journal of bacteriology · 2007Article
- C-terminal WxL domain mediates cell wall binding in Enterococcus faecalis and other gram-positive bacteria.Journal of bacteriology · 2007Article
- The response regulator CroR modulates expression of the secreted stress-induced SalB protein in Enterococcus faecalis.Journal of bacteriology · 2006Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Enterococcus faecalis general stress protein Gsp65 has been purified from two-dimensional gel electrophoresis. Determination of its N-terminal sequence and characterization of the corresponding gene revealed that the gsp65 product is a 133-amino-acid protein sharing homologies with organic hydroperoxide resistance (Ohr) proteins. Transcriptional analysis of gsp65 gave evidence for a monocistronic mRNA initiated 52 nucleotides upstream of the ATG start codon and for an induction in response to hydrogen peroxide, heat shock, acid pH, detergents, ethanol, sodium chloride, and tert-butylhydroperoxide (tBOOH). A gsp65 mutant showed increased sensitivity to the organic hydroperoxide tBOOH and to ethanol.
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