ArticleGenetics2001
Joint linkage and linkage disequilibrium mapping in natural populations.
Article in Genetics, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed.
- MAGIC populations: a next-generation framework for dissecting complex quantitative traits and accelerating molecular breeding in crops.Frontiers in plant science · 2026Review
- The Genetic Architecture of Juvenile Growth Traits in the ConiferFrontiers in plant science · 2022Article
- Narrow genetic base shapes population structure and linkage disequilibrium in an industrial oilseed crop, Brassica carinata A. Braun.Scientific reports · 2020Article
- Association mapping of drought tolerance-related traits in barley to complement a traditional biparental QTL mapping study.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- Crop wild relative populations of Beta vulgaris allow direct mapping of agronomically important genes.Nature communications · 2017Article
- Multi-marker linkage disequilibrium mapping of quantitative trait loci.Briefings in bioinformatics · 2017Article
- Constructing a linkage-linkage disequilibrium map using dominant-segregating markers.DNA research : an international journal for rapid publication of reports on genes and genomes · 2016Article
- Mapping complex traits as a dynamic system.Physics of life reviews · 2015Review
- Association and Validation of Yield-Favored Alleles in Chinese Cultivars of Common Wheat (Triticumaestivum L.).PloS one · 2015Article
- Bayesian model selection for multiple QTLs mapping combining linkage disequilibrium and linkage.Genetics research · 2014Article
- A combined linkage and regional association mapping validation and fine mapping of two major pleiotropic QTLs for seed weight and silique length in rapeseed (Brassica napus L.).BMC plant biology · 2014Article
- Genome-wide two-marker linkage disequilibrium mapping of quantitative trait loci.BMC genetics · 2014Article
- Genetic diversity and population structure in the US Upland cotton (Gossypium hirsutum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2014Article
- Systems mapping of HIV-1 infection.BMC genetics · 2012Article
- Mapping QTL for agronomic traits in breeding populations.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2012Review
- Inheritance of long staple fiber quality traits of Gossypium barbadense in G. hirsutum background using CSILs.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2012Article
- Model and algorithm for linkage disequilibrium analysis in a non-equilibrium population.Frontiers in genetics · 2012Article
- Joint linkage-linkage disequilibrium mapping is a powerful approach to detecting quantitative trait loci underlying drought tolerance in maize.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Sex-specific population structure, natural selection, and linkage disequilibrium in a wild bird population as revealed by genome-wide microsatellite analyses.BMC evolutionary biology · 2010Article
- Association mapping: critical considerations shift from genotyping to experimental design.The Plant cell · 2009Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
A new strategy for studying the genome structure and organization of natural populations is proposed on the basis of a combined analysis of linkage and linkage disequilibrium using known polymorphic markers. This strategy exploits a random sample drawn from a panmictic natural population and the open-pollinated progeny of the sample. It is established on the principle of gene transmission from the parental to progeny generation during which the linkage between different markers is broken down due to meiotic recombination. The strategy has power to simultaneously capture the information about the linkage of the markers (as measured by recombination fraction) and the degree of their linkage disequilibrium created at a historic time. Simulation studies indicate that the statistical method implemented by the Fisher-scoring algorithm can provide accurate and precise estimates for the allele frequencies, recombination fractions, and linkage disequilibria between different markers. The strategy has great implications for constructing a dense linkage disequilibrium map that can facilitate the identification and positional cloning of the genes underlying both simple and complex traits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.