ReviewOncogene2000
BRCA1 and cell signaling.
Review in Oncogene, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 86 citations in OpenAlex.
- Significant association of BRCA1 (rs1799950), BRCA2 (rs144848) and TP53 (rs1042522) polymorphism with breast cancer risk in Pashtun population of Khyber Pakhtunkhwa, Pakistan.Molecular biology reports · 2023Article
- Obesity partially potentiates dimethylbenz[a]anthracene-exposed ovotoxicity by altering the DNA damage repair response in mice†.Biology of reproduction · 2023Article
- Hallmarks of cancer: The insulin-like growth factors perspective.Frontiers in oncology · 2022Review
- Schleichera oleosa Seed Extract Reduced the Proliferation of Breast Cancer by Regulating the BRCA1 and p16 Genes.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Exploiting DNA Damage Repair in Precision Cancer Therapy: BRCA1 as a Prime Therapeutic Target.Cancers · 2021Review
- Peptide microarray of pediatric acute myeloid leukemia is related to relapse and reveals involvement of DNA damage response and repair.Oncotarget · 2019Article
- Identification of BRCA1 As a Potential Biomarker for Insulin-Like Growth Factor-1 Receptor Targeted Therapy in Breast Cancer.Frontiers in endocrinology · 2017Article
- Insulin-like Growth Factor 1 Signaling Axis Meets p53 Genome Protection Pathways.Frontiers in oncology · 2016Review
- Insulin-like growth factor and epidermal growth factor signaling in breast cancer cell growth: focus on endocrine resistant disease.Analytical cellular pathology (Amsterdam) · 2015Review
- BRCA1 polymorphisms and breast cancer epidemiology in the Western New York exposures and breast cancer (WEB) study.Genetic epidemiology · 2013Article
- Article
- [Therapy selection in patients with advanced bladder cancer. Is molecular biology helpful?].Der Urologe. Ausg. A · 2012Article
- Escaping the cut by restriction enzymes through single-strand self-annealing of host-edited 12-bp and longer synthetic palindromes.DNA and cell biology · 2012Article
- Progress in personalizing chemotherapy for bladder cancer.Advances in urology · 2012Article
- Turnover of BRCA1 involves in radiation-induced apoptosis.PloS one · 2010Article
- Tumor suppressor BRCA1 is expressed in prostate cancer and controls insulin-like growth factor I receptor (IGF-IR) gene transcription in an androgen receptor-dependent manner.Clinical cancer research : an official journal of the American Association for Cancer Research · 2009Article
- Metabolic syndrome in sub-Saharan Africa: "smaller twin" of a region's prostatic diseases?International urology and nephrology · 2008Article
- E2F regulates FASCIATA1, a chromatin assembly gene whose loss switches on the endocycle and activates gene expression by changing the epigenetic status.Plant physiology · 2007Article
- BRCA1 Expression is an Important Biomarker for Chemosensitivity: Suppression of BRCA1 Increases the Apoptosis via Up-regulation of p53 and p21 During Cisplatin Treatment in Ovarian Cancer Cells.Biomarker insights · 2007Article
- Absence of the common IGF1 19 CA-repeat allele is more common among BRCA1 mutation carriers than among non-carriers from BRCA1 families.Familial cancer · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The breast cancer and ovarian cancer susceptibility gene BRCA1 encodes a nucleoprotein whose mutations or aberrant expression is associated with both inherited and sporadic cancers. Studies over the last 6 years have suggested that BRCA1 may function as a scaffold in the assembly of a multi-protein complex, which plays a role in gene transcription, DNA damage repair, and transcription-coupled DNA damage repair. In this review, we discuss the implications drawn from the studies of BRCA1-interacting proteins and the cellular signaling pathways that may be involved in controlling the functions of BRCA1.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.