ArticleThe Plant cell2000
A segmental gene duplication generated differentially expressed myb-homologous genes in maize.
Article in The Plant cell, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed.
- SbC1, an R2R3-MYB transcription factor, specifically regulates anthocyanin accumulation in sorghum coleoptiles.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Regulation of Flavonoid Biosynthesis by the MYB-bHLH-WDR (MBW) Complex in Plants and Its Specific Features in Cereals.International journal of molecular sciences · 2025Review
- AcMYB266, a key regulator of the red coloration in pineapple peel: a case of subfunctionalization in tandem duplicated genes.Horticulture research · 2024Article
- An ARF gene mutation creates flint kernel architecture in dent maize.Nature communications · 2024Article
- Genetic analysis of pericarp pigmentation variation in Corn Belt dent maize.G3 (Bethesda, Md.) · 2023Article
- An LcMYB111-LcHY5 Module Differentially Activates anInternational journal of molecular sciences · 2023Article
- Functional characterization of DcMYB11, an R2R3 MYB associated with the purple pigmentation of carrot petiole.Planta · 2023Article
- Article
- Maize Flavonoid Biosynthesis, Regulation, and Human Health Relevance: A Review.Molecules (Basel, Switzerland) · 2022Review
- Exploring theFrontiers in plant science · 2022Article
- Article
- Genome-wide analysis of R2R3-MYB transcription factors family in the autopolyploid Saccharum spontaneum: an exploration of dominance expression and stress response.BMC genomics · 2021Article
- Article
- Systematic Analysis of the R2R3-MYB Family inFrontiers in plant science · 2021Article
- KeyPeerJ · 2021Article
- Ectopic Expression of a Maize Gene Is Induced by Composite Insertions Generated Through Alternative Transposition.Genetics · 2020Article
- Mutually Regulated AP2/ERF Gene Clusters Modulate Biosynthesis of Specialized Metabolites in Plants.Plant physiology · 2020Article
- The R2R3-MYB transcription factor GhMYB1a regulates flavonol and anthocyanin accumulation inHorticulture research · 2020Article
- Characterization of Maize Near-Isogenic Lines With Enhanced Flavonoid Expression to Be Used as Tools in Diet-Health Complexity.Frontiers in plant science · 2020Article
- Gene and Chromosomal Copy Number Variations as an Adaptive Mechanism Towards a Parasitic Lifestyle in Trypanosomatids.Current genomics · 2018Review
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The myb-homologous p1 gene regulates the synthesis of flavonoid pigments in maize kernel pericarp and cob; these floral organs are greatly modified in size and shape compared with their counterparts in teosinte, the progenitor of maize. To elucidate the molecular evolution of the p1 gene in relation to its expression and possible functions in maize and teosinte, we have isolated a second maize gene (p2) that is highly homologous with the p1 gene, and a related gene (p2-t) from Zea mays subsp parviglumis. We present evidence that the maize p1 and p2 genes were generated by duplication of an ancestral p gene (p(pre)) and its downstream sequences; the duplicated 3' flanking sequences were inserted upstream of the p(pre) gene, thereby changing its transcription pattern. This model accounts for the structural organization and the observed differential expression of the p1 and p2 genes: p1 transcripts accumulate in kernel pericarp, cob, tassel glumes, and silk, whereas p2 transcripts are found in developing anther and silk. The duplication is estimated to have occurred 2.75 million years ago; subsequently, multiple retroelements have been inserted between the p1 and p2 genes. Our results demonstrate the evolution of a single gene into a compound locus containing two component genes with different tissue specificities. Expression of the p1 gene in the kernel pericarp may have provided a selective advantage during the evolution of maize kernel morphology.
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