ArticleRNA (New York, N.Y.)2000
Nuclease protection of RNAs containing site-specific labels: a rapid method for mapping RNA-protein interactions.
Article in RNA (New York, N.Y.), 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Definer: A computational method for accurate identification of RNA pseudouridine sites based on deep learning.PloS one · 2025Article
- U1 snRNA directly interacts with polypyrimidine tract-binding protein during splicing repression.Molecular cell · 2011Article
- FragSeq: transcriptome-wide RNA structure probing using high-throughput sequencing.Nature methods · 2010Article
- Dynamic regulation of alternative splicing by silencers that modulate 5' splice site competition.Cell · 2008Article
- Retroviral splicing suppressor sequesters a 3' splice site in a 50S aberrant splicing complex.Molecular and cellular biology · 2005Article
- Spatial organization of protein-RNA interactions in the branch site-3' splice site region during pre-mRNA splicing in yeast.Molecular and cellular biology · 2003Article
- Multiple roles for SR proteins in trans splicing.Molecular and cellular biology · 2002Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
This report describes a method that combines nuclease protection and site-specific labeling to determine sites and extents of RNA-protein interactions. The utility of the method is demonstrated by the analysis of the binding of factors to the 3' splice site region of a pre-mRNA labeled at three specific positions. This "reverse footprinting" technique should be widely applicable to a variety of questions concerning RNA-protein interactions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.