ArticleSexually transmitted infections2000
Low diagnostic accuracy of selective screening criteria for asymptomatic Chlamydia trachomatis infections in the general population.
Article in Sexually transmitted infections, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- The global prevalence of Chlamydia trachomatis genital infection in pregnant women: a meta-analysis.Archives of gynecology and obstetrics · 2025Pooled it
- Socioeconomic factors and other sources of variation in the prevalence of genital chlamydia infections: A systematic review and meta-analysis.BMC public health · 2015Pooled it
- Genital chlamydia prevalence in Europe and non-European high income countries: systematic review and meta-analysis.PloS one · 2015Pooled it
- Chlamydia prevalence in the general population: is there a sex difference? a systematic review.BMC infectious diseases · 2013Pooled it
- Home screening for sexually transmitted diseases in high-risk young women: randomised controlled trial.Sexually transmitted infections · 2007Trial
- TLR2, TLR4 and TLR9 genotypes and haplotypes in the susceptibility to and clinical course of Chlamydia trachomatis infections in Dutch women.Pathogens and disease · 2016Article
- A sexually transmitted infection screening algorithm based on semiparametric regression models.Statistics in medicine · 2015Article
- Population based study of genital Chlamydia trachomatis prevalence and associated factors in Norway: a cross sectional study.BMC infectious diseases · 2012Article
- Evaluation of sexual history-based screening of anatomic sites for chlamydia trachomatis and neisseria gonorrhoeae infection in men having sex with men in routine practice.BMC infectious diseases · 2011Article
- Sexual and reproductive health behaviors of undocumented migrants in Geneva: a cross sectional study.Journal of immigrant and minority health · 2011Article
- Chlamydial infection among patients attending STD and genitourinary clinics in Taiwan.BMC public health · 2007Article
- A prediction rule for selective screening of Chlamydia trachomatis infection.Sexually transmitted infections · 2005Article
- Chlamydial infection: an accurate model for opportunistic screening in general practice.Sexually transmitted infections · 2003Article
- Opportunistic screening for genital chlamydial infection. I: acceptability of urine testing in primary and secondary healthcare settings.Sexually transmitted infections · 2003Article
- Follow-up, treatment, and reinfection rates among asymptomatic chlamydia trachomatis cases in general practice.The British journal of general practice : the journal of the Royal College of General Practitioners · 2002Article
- Notice of redundancy.Sexually transmitted infections · 2001Article
- Cost effectiveness analysis of a population based screening programme for asymptomatic Chlamydia trachomatis infections in women by means of home obtained urine specimens.Sexually transmitted infections · 2001Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo develop and validate selective screening criteria for asymptomatic Chlamydia trachomatis infections in the general population.
methods11,505 people, aged 15-40 years, registered in 16 general practices in Amsterdam were invited to return by mail a home obtained first void urine sample and a questionnaire. Participants were randomly allocated into a development group (75%) or a validation group (25%). C trachomatis infection was determined by the ligase chain reaction. In the development group a set of criteria was identified by means of stepwise logistic regression analysis. The diagnostic accuracy (area under the ROC curve; AUC) and sensitivity, and the corresponding percentage of people selected for screening were calculated. The criteria developed in this study were applied to the validation group.
resultsThe prevalence of asymptomatic C trachomatis infections among men was found to be 2.4% (1.7-3.0), and among women 2.8% (2.2-3.4). Screening men, based on Surinam/Antillean origin and painful micturition, yielded an AUC of 0.58 (0.55-0.60). Screening women, based on Surinam/Antillean origin, new sex partner in the previous 2 months, and unmarried/not cohabiting, yielded an AUC of 0.67 (0.65-0.69). Application of the criteria for men to the validation group yielded an AUC of 0.53 (0.48-0.57); by screening 10% of the men, 15% of the cases were detected. The AUC of the criteria for women in the validation group was 0.58 (0.54-0.61); by screening 51% of the women, 63% of the cases were detected.
conclusionThe prevalence of asymptomatic C trachomatis infections in Amsterdam is less than 3%. No suitable selective screening criteria for the general population could be identified.
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