Evidence map›Paper›PMID 11139515›Full record

ArticleGenetics2001

Duplication and suppression of chloroplast protein translocation genes in maize.

A M Settles, A Baron, A Barkan, R A Martienssen

Abstract read
In one paragraph

Article in Genetics, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The expanding world of small RNAs in plants.Nature reviews. Molecular cell biology · 2015
    Review
  5. Article
  6. Article
  7. Maize-targeted mutagenesis: A knockout resource for maize.Proceedings of the National Academy of Sciences of the United States of America · 2003
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

A M SettlesCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
A Baron
A Barkan
R A Martienssen
Cold Spring Harbor Laboratory · USUniversity of Oregon · US

Funding

NUCLEAR GENES THAT MEDIATE CHLOROPLAST ASSEMBLYR01GM048179 · NIGMS · UNIVERSITY OF OREGON · PI BARKAN, ALICE · 1997 to 2000
$188k
NIGMS NIH HHS R01 GM48179
6 · The paper itself

Abstract

The HCF106 (high chlorophyll fluorescence) gene of maize encodes a chloroplast membrane protein required for translocation of a subset of proteins across the thylakoid membrane. Mutations in HCF106 caused by the insertion of Robertson's Mutator transposable elements have been mapped to chromosome 2S. Here we show that there is a closely related homolog of HCF106 encoded elsewhere in the maize genome (HCF106c) that can partially compensate for these mutations. This homolog maps on chromosome 10L and is part of the most recent set of segmental duplications in the maize genome. Triple mutants that are disrupted in both the HCF106 and Sec-dependent protein translocation pathways provide evidence that they act independently. The HCF106c gene accounts for a previously reported exception to the correlation between epigenetic suppression of hcf106 and methylation of Mutator transposons. We also demonstrate that insertions of Robertson's Mutator elements into either introns or promoters can lead to mutations whose phenotypes are suppressed in the absence of Mu activity, while alleles with insertions in both positions are not suppressed. The implications of these observations are discussed.

Indexed as

Genes, PlantAllelesAmino Acid SequenceBase SequenceBiological Transport, ActiveChloroplastsCloning, MolecularDNA, PlantDNA PrimersDNA Transposable ElementsGene DuplicationIntronsMembrane ProteinsModels, GeneticMolecular Sequence DataMutationDNA, PlantDNA PrimersDNA Transposable ElementsHcf106 protein, plantMembrane ProteinsPlant Proteins

Identifiers

PMID11139515
PMCPMC1461481
OpenAlexW2127592359

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.