ArticleThe Journal of general physiology2001
Light adaptation in Drosophila photoreceptors: I. Response dynamics and signaling efficiency at 25 degrees C.
Article in The Journal of general physiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.
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Who cites it
77 citing papers in PubMed.
- Spontaneous spiking in photoreceptors of Periplaneta americana.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Article
- Photoreceptor recordings reveal remarkable acuity in small solitary bees compared with larger species.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Light adaptation of the microvillus refractory period in blow fly photoreceptors.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Article
- Synaptic high-frequency jumping synchronises vision to high-speed behaviour.Nature communications · 2026Article
- Analysis of inductance-like effects of delayed rectifiers: amplification of voltage response onset, acceleration of decay, and voltage- and kinetics-dependent limitations.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2025Article
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- A recurrent neural circuit in Drosophila temporally sharpens visual inputs.Current biology : CB · 2025Article
- A recurrent neural circuit inbioRxiv : the preprint server for biology · 2024Article
- Direct comparison reveals algorithmic similarities in fly and mouse visual motion detection.iScience · 2023Article
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- Stimulator compensation and generation of Gaussian noise stimuli with defined amplitude spectra for studying input-output relations of sensory systems.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2023Article
- A Quantitative Model of Sporadic Axonal Degeneration in theThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- High-speed imaging of light-induced photoreceptor microsaccades in compound eyes.Communications biology · 2022Article
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- Night skies through animals' eyes-Quantifying night-time visual scenes and light pollution as viewed by animals.Frontiers in cellular neuroscience · 2022Article
- Predicting individual neuron responses with anatomically constrained task optimization.Current biology : CB · 2021Article
- Temporal vision: measures, mechanisms and meaning.The Journal of experimental biology · 2021Article
- Speed of phototransduction in the microvillus regulates the accuracy and bandwidth of the rhabdomeric photoreceptor.PLoS computational biology · 2020Article
- Active vision shapes and coordinates flight motor responses in flies.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Seeing Natural Images through the Eye of a Fly with Remote Focusing Two-Photon Microscopy.iScience · 2020Article
17 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors.
Funding
Abstract
Besides the physical limits imposed on photon absorption, the coprocessing of visual information by the phototransduction cascade and photoreceptor membrane determines the fidelity of photoreceptor signaling. We investigated the response dynamics and signaling efficiency of Drosophila photoreceptors to natural-like fluctuating light contrast stimulation and intracellular current injection when the cells were adapted over a 4-log unit light intensity range at 25 degrees C. This dual stimulation allowed us to characterize how an increase in the mean light intensity causes the phototransduction cascade and photoreceptor membrane to produce larger, faster and increasingly accurate voltage responses to a given contrast. Using signal and noise analysis, this appears to be associated with an increased summation of smaller and faster elementary responses (i.e., bumps), whose latency distribution stays relatively unchanged at different mean light intensity levels. As the phototransduction cascade increases, the size and speed of the signals (light current) at higher adapting backgrounds and, in conjunction with the photoreceptor membrane, reduces the light-induced voltage noise, and the photoreceptor signal-to-noise ratio improves and extends to a higher bandwidth. Because the voltage responses to light contrasts are much slower than those evoked by current injection, the photoreceptor membrane does not limit the speed of the phototransduction cascade, but it does filter the associated high frequency noise. The photoreceptor information capacity increases with light adaptation and starts to saturate at approximately 200 bits/s as the speed of the chemical reactions inside a fixed number of transduction units, possibly microvilli, is approaching its maximum.
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