ArticleNucleic acids research2001
Collecting and harvesting biological data: the GPCRDB and NucleaRDB information systems.
Article in Nucleic acids research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed.
- SEVENS: a database for comprehensive GPCR genes obtained from genomes: -Update to 68 eukaryotes.Biophysics and physicobiology · 2018Article
- GPCRdb: an information system for G protein-coupled receptors.Nucleic acids research · 2016Article
- SVM-Prot 2016: A Web-Server for Machine Learning Prediction of Protein Functional Families from Sequence Irrespective of Similarity.PloS one · 2016Article
- Accurate prediction of nuclear receptors with conjoint triad feature.BMC bioinformatics · 2015Article
- NRfamPred: a proteome-scale two level method for prediction of nuclear receptor proteins and their sub-families.Scientific reports · 2014Article
- Drug target mining and analysis of the Chinese tree shrew for pharmacological testing.PloS one · 2014Article
- GPCRDB: an information system for G protein-coupled receptors.Nucleic acids research · 2014Article
- Top-down clustering for protein subfamily identification.Evolutionary bioinformatics online · 2013Article
- NucleaRDB: information system for nuclear receptors.Nucleic acids research · 2012Article
- iNR-PhysChem: a sequence-based predictor for identifying nuclear receptors and their subfamilies via physical-chemical property matrix.PloS one · 2012Article
- Molecular mechanisms of disease for mutations at Gly-90 in rhodopsin.The Journal of biological chemistry · 2011Article
- Chemical structural novelty: on-targets and off-targets.Journal of medicinal chemistry · 2011Article
- Discovery-driven research and bioinformatics in nuclear receptor and coregulator signaling.Biochimica et biophysica acta · 2011Review
- NR-2L: a two-level predictor for identifying nuclear receptor subfamilies based on sequence-derived features.PloS one · 2011Article
- PROFESS: a PROtein function, evolution, structure and sequence database.Database : the journal of biological databases and curation · 2010Article
- Physical binding pocket induction for affinity prediction.Journal of medicinal chemistry · 2009Article
- Hmrbase: a database of hormones and their receptors.BMC genomics · 2009Article
- Article
- Adenosine induces growth-cone turning of sensory neurons.Purinergic signalling · 2008Article
- Searching for factors that distinguish disease-prone and disease-resistant prions via sequence analysis.Bioinformatics and biology insights · 2008Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The amount of genomic and proteomic data that is entered each day into databases and the experimental literature is outstripping the ability of experimental scientists to keep pace. While generic databases derived from automated curation efforts are useful, most biological scientists tend to focus on a class or family of molecules and their biological impact. Consequently, there is a need for molecular class-specific or other specialized databases. Such databases collect and organize data around a single topic or class of molecules. If curated well, such systems are extremely useful as they allow experimental scientists to obtain a large portion of the available data most relevant to their needs from a single source. We are involved in the development of two such databases with substantial pharmacological relevance. These are the GPCRDB and NucleaRDB information systems, which collect and disseminate data related to G protein-coupled receptors and intra-nuclear hormone receptors, respectively. The GPCRDB was a pilot project aimed at building a generic molecular class-specific database capable of dealing with highly heterogeneous data. A first version of the GPCRDB project has been completed and it is routinely used by thousands of scientists. The NucleaRDB was started recently as an application of the concept for the generalization of this technology. The GPCRDB is available via the WWW at http://www.gpcr.org/7tm/ and the NucleaRDB at http://www.receptors.org/NR/.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.