Evidence map›Paper›PMID 11123035›Full record

ReviewCurrent rheumatology reports2000

Atherosclerosis and systemic lupus erythematosus.

M Urowitz, D Gladman, I Bruce

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current rheumatology reports, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Preliminary Report of Endovascular Treatment for Critical Limb Ischemia Patients with Connective Tissue Disease: Cases Series and Review of the Literature.The International journal of angiology : official publication of the International College of Angiology, Inc · 2015
    Article
  5. Statins and autoimmunity.Immunologic research · 2013
    Review
  6. Article
  7. Von Willebrand factor, red cell fragmentation, and disease activity in systemic lupus erythematosus.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2008
    Article
  8. Article
  9. Review
  10. Pathogenesis of atherosclerosis: A multifactorial process.Experimental and clinical cardiology · 2002
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

M UrowitzUniversity of Toronto, Director Centre of Prognosis Studies in The Rheumatic Diseases and The University of Toronto Lupus Clinic, The Toronto Hospital, Western Division, 399 Bathurst Street, 1-318, Toronto, Ontario, M5T 2S8, Canada. urowitz@utoronto.ca
D Gladman
I Bruce
University of Toronto · CAUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The description of late-stage mortality and morbidity has been an important contribution to the understanding of systemic lupus erythematosus (SLE) in the past decade. Among the major factors in this clinical spectrum of SLE is the development of accelerated atherosclerosis. This condition has been recognized clinically with the documentation of myocardial infarction and angina in young women with SLE. This accelerated atherosclerosis has also been recognized at postmortem examinations. The exact mechanism for accelerated atherosclerosis remains unclear. However, disease activity with its immunologic events, the anticardiolipin syndrome, and the effect of corticosteroids in promoting hyperlipidemia contribute to its development. It appears that SLE may be a risk factor, in addition to the usual risk factors for the development of atherosclerosis. It has recently been shown that antimalarials may prevent some of the hyperlipidemia caused by corticosteroids. As evidence for the presence of subclinical atherosclerosis in these patients is accumulating, earlier diagnosis and treatment of events may be possible, and preventive measures may be instituted earlier.

Indexed as

Adrenal Cortex HormonesAntimalarialsArteriosclerosisComorbidityFemaleHumansIncidenceLupus Erythematosus, SystemicMalePrognosisRisk AssessmentRisk FactorsSurvival RateAdrenal Cortex HormonesAntimalarials

Identifiers

PMID11123035
OpenAlexW2088086464

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.