SynthesisCurrent atherosclerosis reports1999
Nut consumption and risk of coronary heart disease: a review of epidemiologic evidence.
Synthesis in Current atherosclerosis reports, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 187 citations in OpenAlex.
- The Effect of Nut Consumption on Diet Quality, Cardiometabolic and Gastrointestinal Health in Children: A Systematic Review of Randomized Controlled Trials.International journal of environmental research and public health · 2021Pooled it
- Nut consumption and risk of cancer and type 2 diabetes: a systematic review and meta-analysis.Nutrition reviews · 2015Pooled it
- Effects of walnut consumption on blood lipids and other cardiovascular risk factors: a meta-analysis and systematic review.The American journal of clinical nutrition · 2009Pooled it
- The effect of almonds on vitamin E status and cardiovascular risk factors in Korean adults: a randomized clinical trial.European journal of nutrition · 2018Trial
- Effects of walnut oil on lipid profiles in hyperlipidemic type 2 diabetic patients: a randomized, double-blind, placebo-controlled trial.Nutrition & diabetes · 2017Trial
- Effects of daily almond consumption on cardiometabolic risk and abdominal adiposity in healthy adults with elevated LDL-cholesterol: a randomized controlled trial.Journal of the American Heart Association · 2015Trial
- A randomized trial of the effects of an almond-enriched, hypocaloric diet in the treatment of obesity.The American journal of clinical nutrition · 2012Trial
- Nuts as a replacement for carbohydrates in the diabetic diet.Diabetes care · 2011Trial
- Effect of moderate walnut consumption on lipid profile, arterial stiffness and platelet activation in humans.European journal of clinical nutrition · 2011Trial
- Adding monounsaturated fatty acids to a dietary portfolio of cholesterol-lowering foods in hypercholesterolemia.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2010Trial
- Long-term walnut supplementation without dietary advice induces favorable serum lipid changes in free-living individuals.European journal of clinical nutrition · 2010Trial
- Effects of hazelnut-enriched diet on plasma cholesterol and lipoprotein profiles in hypercholesterolemic adult men.European journal of clinical nutrition · 2007Trial
- Manufacturing plant-based non-dairy and probiotic frozen desserts and their impact on physicochemical, sensory and functional aspects.Journal of food science and technology · 2024Article
- Health Behavior Change Intervention Preferences Expressed by American Indian Cancer Survivors From a Southwest Tribal Community: Semistructured Interview Study.JMIR formative research · 2024Article
- Article
- Recent advances in the use of walnut (RSC advances · 2020Review
- A Comprehensive Review on the Chemical Constituents and Functional Uses of Walnut (International journal of molecular sciences · 2019Review
- A Comparative Review on the Extraction, Antioxidant Content and Antioxidant Potential of Different Parts of Walnut (Molecules (Basel, Switzerland) · 2019Review
- Assessment of Risk Factors and Biomarkers Associated With Risk of Cardiovascular Disease Among Women Consuming a Mediterranean Diet.JAMA network open · 2018Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traditionally nuts have been perceived as an unhealthy food because of their high fat content. However, recent accumulative evidence suggests that frequent consumption of nuts may be protective against coronary heart disease (CHD). So far, five large prospective cohort studies (the Adventist Health Study, the Iowa Women Health Study, the Nurses' Health Study, the Physicians' Health Study, and the CARE Study) have examined the relation between nut consumption and the risk of CHD and all have found an inverse association. In addition, several clinical studies have observed beneficial effects of diets high in nuts (including walnuts, peanuts, almonds, and other nuts) on blood lipids. The beneficial effects of nut consumption observed in clinical and epidemiologic studies underscore the importance of distinguishing different types of fat. Most fats in nuts are mono- and polyunsaturated fats that lower low-density lipoprotein cholesterol level. Based on the data from the Nurses' Health Study, we estimated that substitution of the fat from 1 ounce of nuts for equivalent energy from carbohydrate in an average diet was associated with a 30% reduction in CHD risk and the substitution of nut fat for saturated fat was associated with 45% reduction in risk. Given the strong scientific evidence for the beneficial effects of nuts, it seems justifiable to move nuts to a more prominent place in the United States Department of Agriculture Food Guide Pyramid. Regular nut consumption can be recommended in the context of a healthy and balanced diet.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.