Evidence map›Paper›PMID 11122710›Full record

ReviewCurrent atherosclerosis reports1999

Genetic predictors of plasma lipid response to diet intervention.

J M Ordovas, J R Galluzzi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

J M OrdovasLipid Metabolism Laboratory, JM-USDA-Human Nutrition Research Center on Aging at Tufts University, Department of Medicine, New England Medical Center, Boston, MA, USA.
J R Galluzzi

Funding

GENE/DIET EFFECTS ON PLASMA LIPOPROTEIN LEVELSR01HL054776 · NHLBI · TUFTS UNIVERSITY BOSTON · PI ORDOVAS, JOSE M. · 1996 to 2010
$2.6M
NHLBI NIH HHS HL54776NIA NIH HHS AG00209-09
6 · The paper itself

Abstract

There is a growing interest in determining the genetic predictors of plasma lipid response to diet intervention. Several candidate gene loci, namely, apolipoprotein (APO) A1, APOA4, APOC3, APOB, APOE, CETP, LPL, and FABP2, have been shown to explain a significant, but still rather small, proportion of the interindividual variability in dietary response. Other gene loci code for products that play a relevant role in lipoprotein metabolism and are prime candidates for future studies (ie, CYP7). Future progress in this complex area will come from experiments carried out using animal models and from carefully controlled dietary protocols in humans.

Indexed as

DietGenetic Predisposition to DiseaseNeoplasm ProteinsTumor Suppressor ProteinsApolipoproteinsArteriosclerosisCarrier ProteinsCholesterol 7-alpha-HydroxylaseDietary FatsFatty Acid-Binding Protein 7Fatty Acid-Binding ProteinsHumansLipid MetabolismLipidsApolipoproteinsCarrier ProteinsCholesterol 7-alpha-HydroxylaseDietary FatsFABP2 protein, humanFabp2 protein, mouseFABP7 protein, humanFatty Acid-Binding Protein 7Fatty Acid-Binding ProteinsLipidsNeoplasm ProteinsTumor Suppressor Proteins

Identifiers

PMID11122710

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.