ArticleJournal of virology2001
Cooperative transformation and coexpression of bovine papillomavirus type 1 E5 and E7 proteins.
Article in Journal of virology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 37 citations in OpenAlex.
- Anogenital-Associated Papillomaviruses in Animals: Focusing onPathogens (Basel, Switzerland) · 2020Review
- Detection and phylogenetic analysis of bovine papillomavirus in cutaneous warts in cattle in Tamaulipas, Mexico.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2016Article
- Article
- Bovine papillomavirus on the scene of crime: is E5 oncogene the only guilty party?Infectious agents and cancer · 2013Article
- Bovine papillomavirus E5 and E7 oncoproteins in naturally occurring tumors: are two better than one?Infectious agents and cancer · 2013Article
- Regulation of bovine papillomavirus type 1 gene expression by RNA processing.Frontiers in bioscience (Landmark edition) · 2009Review
- Transformation by bovine papillomavirus type 1 E6 requires paxillin.Journal of virology · 2008Article
- Bovine papillomavirus E7 oncoprotein inhibits anoikis.Journal of virology · 2007Article
- Bovine papillomavirus E7 transformation function correlates with cellular p600 protein binding.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
- P19ARF inhibits the functions of the HPV16 E7 oncoprotein.Oncogene · 2003Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Productively infected bovine fibropapillomas were examined for bovine papillomavirus type 1 (BPV-1) E7 localization. BPV-1 E7 was observed in the cytoplasm of basal and lower spinous epithelial cells, coexpressed in the cytoplasm of basal cells with the E5 oncoprotein. E7 was also observed in nucleoli throughout the basal and spinous layers but not in the granular cell layer. Ectopic expression of E7 in cultured epithelial cells gave rise to localization similar to that seen in productive fibropapillomas, with cytoplasmic and nucleolar expression observed. Consistent with the coexpression of E7 and E5 in basal keratinocytes, BPV-1 E7 cooperated with E5 as well as E6 in an anchorage independence transformation assay. While E5 is expressed in both basal and superficial differentiating keratinocytes, BPV-1 E7 is only observed in basal and lower spinous epithelial cells. Therefore, BPV-1 E7 may serve to modulate the cellular response of basal epithelial cells to E5 expression.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.