ReviewJournal of psychiatry & neuroscience : JPN2000
Neurochemical and metabolic aspects of antidepressants: an overview.
Review in Journal of psychiatry & neuroscience : JPN, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 22 citations in OpenAlex.
- The trace amine theory of spontaneous hypertension as induced by classic monoamine oxidase inhibitors.Journal of neural transmission (Vienna, Austria : 1996) · 2021Article
- Opipramol Inhibits Lipolysis in Human Adipocytes without Altering Glucose Uptake and Differently from Antipsychotic and Antidepressant Drugs with Adverse Effects on Body Weight Control.Pharmaceuticals (Basel, Switzerland) · 2020Article
- Body fat reduction without cardiovascular changes in mice after oral treatment with the MAO inhibitor phenelzine.British journal of pharmacology · 2018Article
- Discrimination Between Drug Abuse and Medical Therapy: Case report of a tranylcypromine overdose-related fatality.Sultan Qaboos University medical journal · 2017Article
- Trace amine-associated receptor 1-Family archetype or iconoclast?Pharmacology & therapeutics · 2007Review
- Tranylcypromine: new perspectives on an "old" drug.European archives of psychiatry and clinical neuroscience · 2006Review
- Mechanisms of 5-aminolevulinic acid ester uptake in mammalian cells.British journal of pharmacology · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antidepressants, in addition to being effective therapeutic agents for depression, have also proved to be multifaceted drugs useful for treating a number of other psychiatric and neurologic disorders. Despite the widespread use of these drugs, much remains to be understood about their mechanisms of action and other important aspects, such as their metabolism and potential interactions with other drugs. This article reviews research conducted in the authors' laboratories on various aspects of antidepressants, including trace amines and antidepressants, gamma-aminobutyric acid and antidepressants, drug metabolism, development and application of rapid, sensitive assay procedures for antidepressants and their metabolites; and drug development based on analogues of the antidepressants phenelzine and tranylcypromine. The significance of this work to future drug development is also discussed.
Indexed as
Identifiers
11109299PMC1408023W2167282979What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.