ArticleThe Biochemical journal2000
Organization, chromosomal localization and promoter analysis of the gene encoding human acidic fibroblast growth factor intracellular binding protein.
Article in The Biochemical journal, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Thauvin-Robinet-Faivre Syndrome: AJournal of clinical research in pediatric endocrinology · 2026Article
- Transcriptional risk scores in Alzheimer's disease: From pathology to cognition.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- FIBP interacts with transcription factor STAT3 to induce EME1 expression and drive radioresistance in lung adenocarcinoma.International journal of biological sciences · 2023Article
- Proteomic analysis of the human cyclin-dependent kinase family reveals a novel CDK5 complex involved in cell growth and migration.Molecular & cellular proteomics : MCP · 2014Article
- FGF-dependent left-right asymmetry patterning in zebrafish is mediated by Ier2 and Fibp1.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Cardiac myocyte differentiation: the Nkx2.5 and Cripto target genes in P19 clone 6 cells.Functional & integrative genomics · 2005Article
- Increase of acidic fibroblast growth factor in the brains of hamsters infected with either 263K or 139H strains of scrapie.Journal of molecular neuroscience : MN · 2002Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acidic fibroblast growth factor (aFGF) intracellular binding protein (FIBP) is a protein found mainly in the nucleus that might be involved in the intracellular function of aFGF. Here we present a comparative analysis of the deduced amino acid sequences of human, murine and Drosophila FIBP analogues and demonstrate that FIBP is an evolutionarily conserved protein. The human gene spans more than 5 kb, comprising ten exons and nine introns, and maps to chromosome 11q13.1. Two slightly different splice variants found in different tissues were isolated and characterized. Sequence analysis of the region surrounding the translation start revealed a CpG island, a classical feature of widely expressed genes. Functional studies of the promoter region with a luciferase reporter system suggested a strong transcriptional activity residing within 600 bp of the 5' flanking region.
Indexed as
Identifiers
11104667PMC1221498W2128148093What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.