ArticleGenetics2000
Heteroplasmy in the mtDNA control region of sturgeon (Acipenser, Huso and Scaphirhynchus).
Article in Genetics, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed.
- Evolutionary patterns of the mitochondrial control region in vertebrates: A large-scale comparative analysis.PloS one · 2026Article
- Characterization of the mitochondrial Huso huso genome and new aspects of its organization in the presence of tandem repeats in 12S rRNA.BMC ecology and evolution · 2023Article
- Species Identification of Caviar Based on Multiple DNA Barcoding.Molecules (Basel, Switzerland) · 2023Article
- Mitogenome-wise codon usage pattern from comparative analysis of the first mitogenome of Blepharipa sp. (Muga uzifly) with other Oestroid flies.Scientific reports · 2022Article
- Chromosome-Level Genome Assembly of the Bioluminescent Cardinalfish Siphamia tubifer: An Emerging Model for Symbiosis Research.Genome biology and evolution · 2022Article
- Molluscan mitochondrial genomes break the rules.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Highly Resolved Phylogenetic Relationships within Order Acipenseriformes According to Novel Nuclear Markers.Genes · 2019Article
- Mind the gap! The mitochondrial control region and its power as a phylogenetic marker in echinoids.BMC evolutionary biology · 2018Article
- Assembly and variation analyses of Clarias batrachus mitogenome retrieved from WGS data and its phylogenetic relationship with other catfishes.Meta gene · 2015Article
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- Site heteroplasmy in the mitochondrial cytochrome b gene of the sterlet sturgeon Acipenser ruthenus.Genetics and molecular biology · 2012Article
- Contrasting evolutionary dynamics and information content of the avian mitochondrial control region and ND2 gene.PloS one · 2012Article
- Managing polyploidy in ex situ conservation genetics: the case of the critically endangered Adriatic sturgeon (Acipenser naccarii).PloS one · 2011Article
- Structure and conservation of tandem repeats in the mitochondrial DNA control region of the Least Brook lamprey (Lampetra aepyptera).Journal of molecular evolution · 2009Article
- Tracing the first steps of American sturgeon pioneers in Europe.BMC evolutionary biology · 2008Article
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- Comparing relative rates of pollen and seed gene flow in the island model using nuclear and organelle measures of population structure.Genetics · 2002Article
- Genome duplication events and functional reduction of ploidy levels in sturgeon (Acipenser, Huso and Scaphirhynchus).Genetics · 2001Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Data from 1238 fishes from 19 sturgeon species and 1 paddlefish were used to analyze heteroplasmy in sturgeon. Lengths of central repeat units ranged from 74 to 83 bp among sturgeon species. No repeat sequence was found in the paddlefish, Polyodon spathula. A general feature of the repeat units was the presence of termination associated sequence (TAS) motifs. About 50% of 138 interspecific mutations observed among the D-loop sequences are located 10 bp down- and upstream from these TAS motifs. Interestingly, most homoplasmic species showed deletions upstream to the TAS motifs, whereas deletions downstream to the TAS motifs observed in two species do not seem to preclude heteroplasmy. Calculations of secondary structures and thermal stabilities of repeat units showed DeltaG values for all heteroplasmic species to be <-8 and for most homoplasmic species DeltaG value to be >-8. Most heteroplasmic fishes had two and/or three repeat units. No homoplasmic sturgeon with >2 repeat units were observed. Molecular phylogeny based on the entire cytochrome b showed that heteroplasmy probably resulted from a single evolutionary event. Our data demonstrate that heteroplasmy is present in most sturgeon species and suggest that the thermal stability of the secondary structure of the repeat unit in combination with mutations downstream of the TAS sequences influences heteroplasmy.
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