ArticleGenetics2000
A selective sweep associated with a recent gene transposition in Drosophila miranda.
Article in Genetics, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Article
- Genome-wide analysis of retrogene polymorphisms in Drosophila melanogaster.Genome research · 2011Article
- Many or most genes in Arabidopsis transposed after the origin of the order Brassicales.Genome research · 2008Article
- A new retroposed gene in Drosophila heterochromatin detected by microarray-based comparative genomic hybridization.Journal of molecular evolution · 2007Article
- Evolution of amino-acid sequences and codon usage on the Drosophila miranda neo-sex chromosomes.Genetics · 2006Article
- Rates and patterns of chromosomal evolution in Drosophila pseudoobscura and D. miranda.Genetics · 2006Article
- Article
- On the genomic location of the exuperantia1 gene in Drosophila miranda: the limits of in situ hybridization experiments.Genetics · 2003Article
- Dntf-2r, a young Drosophila retroposed gene with specific male expression under positive Darwinian selection.Genetics · 2003Article
- Article
- Regions of lower crossing over harbor more rare variants in African populations of Drosophila melanogaster.Genetics · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Drosophila miranda, a chromosome fusion between the Y chromosome and the autosome corresponding to Muller's element C has created a new sex chromosome system. The chromosome attached to the ancestral Y chromosome is transmitted paternally and hence is not exposed to crossing over. This chromosome, conventionally called the neo-Y, and the homologous neo-X chromosome display many properties of evolving sex chromosomes. We report here the transposition of the exuperantia1 (exu1) locus from a neo-sex chromosome to the ancestral X chromosome of D. miranda. Exu1 is known to have several critical developmental functions, including a male-specific role in spermatogenesis. The ancestral location of exu1 is conserved in the sibling species of D. miranda, as well as in a more distantly related species. The transposition of exu1 can be interpreted as an adaptive fixation, driven by a selective advantage conferred by its effect on dosage compensation. This explanation is supported by the pattern of within-species sequence variation at exu1 and the nearby exu2 locus. The implications of this phenomenon for genome evolution are discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.