Do inactivation mechanisms rather than adaptation hold the key to understanding ryanodine receptor channel gating?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed.

1. CaeLife · 2022
   Article
2. The cellular force-frequency response in ventricular myocytes from the varanid lizard, Varanus exanthematicus.American journal of physiology. Regulatory, integrative and comparative physiology · 2010
   Article
3. Calcium signaling phenomena in heart diseases: a perspective.Molecular and cellular biochemistry · 2007
   Review
4. Altered intracellular Ca2+ handling in heart failure.The Journal of clinical investigation · 2005
   Review
5. Calcium regulation of single ryanodine receptor channel gating analyzed using HMM/MCMC statistical methods.The Journal of general physiology · 2004
   Article
6. Return of calcium: manipulating intracellular calcium to prevent cardiac pathologies.Proceedings of the National Academy of Sciences of the United States of America · 2004
   Article
7. Termination of cardiac Ca(2+) sparks: an investigative mathematical model of calcium-induced calcium release.Biophysical journal · 2002
   Article
8. Alkyl Mercury-Induced Toxicity: Multiple Mechanisms of Action.Reviews of environmental contamination and toxicology
   Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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