Trial reportBMJ (Clinical research ed.)2000
Randomised controlled trial of non-directive counselling, cognitive-behaviour therapy, and usual general practitioner care for patients with depression. I: clinical effectiveness.
Trial report in BMJ (Clinical research ed.), 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 12 syntheses or guidelines pooled it, 245 citations in OpenAlex.
- The impact of patient choice on uptake, adherence, and outcomes across depression, anxiety, and eating disorders: a systematic review and meta-analysis.Psychological medicine · 2025Pooled it
- Association of Patient Treatment Preference With Dropout and Clinical Outcomes in Adult Psychosocial Mental Health Interventions: A Systematic Review and Meta-analysis.JAMA psychiatry · 2020Pooled it
- Cognitive behavioral therapy for primary care depression and anxiety: a secondary meta-analytic review using robust variance estimation in meta-regression.Journal of behavioral medicine · 2019Pooled it
- Effectiveness of Dance Movement Therapy in the Treatment of Adults With Depression: A Systematic Review With Meta-Analyses.Frontiers in psychology · 2019Pooled it
- Evidence-based, non-pharmacological treatment guideline for depression in Korea.Journal of Korean medical science · 2014Guideline
- Brief psychotherapy for depression: a systematic review and meta-analysis.International journal of psychiatry in medicine · 2012Pooled it
- Counselling for mental health and psychosocial problems in primary care.The Cochrane database of systematic reviews · 2011Pooled it
- Brief psychological therapies for anxiety and depression in primary care: meta-analysis and meta-regression.BMC medicine · 2010Pooled it
- On-site mental health workers delivering psychological therapy and psychosocial interventions to patients in primary care: effects on the professional practice of primary care providers.The Cochrane database of systematic reviews · 2009Pooled it
- Depression in adults: psychological treatments and care pathways.BMJ clinical evidence · 2007Pooled it
- Primary care mental health workers: models of working and evidence of effectiveness.The British journal of general practice : the journal of the Royal College of General Practitioners · 2002Pooled it
- The clinical and cost-effectiveness of self-help treatments for anxiety and depressive disorders in primary care: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2001Pooled it
- Can General Practitioners manage mental disorders in primary care? A partially randomised, pragmatic, cluster trial.PloS one · 2019Trial
- Adverse effects from antidepressant treatment: randomised controlled trial of 601 depressed individuals.Psychopharmacology · 2014Trial
- Guided self-help cognitive behavioural therapy for depression in primary care: a randomised controlled trial.PloS one · 2013Trial
- Acupuncture, Counseling, and Usual care for Depression (ACUDep): study protocol for a randomized controlled trial.Trials · 2012Trial
- Factors associated with attrition from a randomized controlled trial of meaning-centered group psychotherapy for patients with advanced cancer.Psycho-oncology · 2012Trial
- Internet-based cognitive behaviour therapy for obsessive-compulsive disorder: a randomized controlled trial.Psychological medicine · 2012Trial
- Results of a randomized controlled trial of mental illness self-management using Wellness Recovery Action Planning.Schizophrenia bulletin · 2012Trial
- Depression beliefs, treatment preference, and outcomes in a randomized trial for major depressive disorder.Journal of psychiatric research · 2012Trial
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare the clinical effectiveness of general practitioner care and two general practice based psychological therapies for depressed patients.
designProspective, controlled trial with randomised and patient preference allocation arms.
settingGeneral practices in London and greater Manchester.
participants464 of 627 patients presenting with depression or mixed anxiety and depression were suitable for inclusion.
interventionsUsual general practitioner care or up to 12 sessions of non-directive counselling or cognitive-behaviour therapy provided by therapists.
main outcome measuresBeck depression inventory scores, other psychiatric symptoms, social functioning, and satisfaction with treatment measured at baseline and at 4 and 12 months.
results197 patients were randomly assigned to treatment, 137 chose their treatment, and 130 were randomised only between the two psychological therapies. All groups improved significantly over time. At four months, patients randomised to non-directive counselling or cognitive-behaviour therapy improved more in terms of the Beck depression inventory (mean (SD) scores 12.9 (9.3) and 14.3 (10.8) respectively) than those randomised to usual general practitioner care (18.3 (12.4)). However, there was no significant difference between the two therapies. There were no significant differences between the three treatment groups at 12 months (Beck depression scores 11.8 (9.6), 11.4 (10.8), and 12.1 (10.3) for non-directive counselling, cognitive-behaviour therapy, and general practitioner care).
conclusionsPsychological therapy was a more effective treatment for depression than usual general practitioner care in the short term, but after one year there was no difference in outcome.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.