ReviewCritical care (London, England)2000
Understanding gastrointestinal perfusion in critical care: so near, and yet so far.
Review in Critical care (London, England), 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- A review of gut failure as a cause and consequence of critical illness.Critical care (London, England) · 2025Review
- CRRT Is More Than Just Continuous Renal Replacement Therapy.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Incidence of Acute Upper Gastrointestinal Bleeding and Related Risk Factors among Elderly Patients Undergoing Surgery for Major Limb Fractures: An Analytical Cohort Study.Healthcare (Basel, Switzerland) · 2023Article
- The leaky gut and the gut microbiome in sepsis - targets in research and treatment.Clinical science (London, England : 1979) · 2023Article
- Drug-Induced Hyperthermia Review.Cureus · 2022Review
- Should we routinely prescribe proton pump inhibitors peri-operatively in elderly patients with hip fractures? A review of the literature.EFORT open reviews · 2021Review
- A Clinician's Guide to Dosing Analgesics, Anticonvulsants, and Psychotropic Medications in Continuous Renal Replacement Therapy.Kidney international reports · 2021Review
- Circulatory Failure among Hospitalizations for Heatstroke in the United States.Medicines (Basel, Switzerland) · 2020Article
- Fulminant Necrotizing Enterocolitis and Multiple Organ Dysfunction in a Toddler with Mitochondrial DNA Depletion Syndrome-13.Journal of pediatric intensive care · 2020Article
- Exogenous vasopressin dose-dependently modulates gastric microcirculatory oxygenation in dogs via V1A receptor.Critical care (London, England) · 2019Article
- Myogenic tone contributes to the regulation of permeability in mesenteric microvessels.Microvascular research · 2019Article
- Probiotics, prebiotics and amelioration of diseases.Journal of biomedical science · 2019Review
- Effects of cisatracurium in combination with ventilation on inflammatory factors and immune variations in sepsis rats.Experimental and therapeutic medicine · 2018Article
- Role of matrix metalloproteinase-8 as a mediator of injury in intestinal ischemia and reperfusion.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2016Article
- Recent Advances of Mucosal Capnometry and the Perspectives of Gastrointestinal Monitoring in the Critically Ill. A Pilot Study.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2016Article
- Monitoring CO2 in shock states.Journal of clinical monitoring and computing · 2015Review
- Restrictive Fluid Resuscitation Leads to Better Oxygenation than Non-Restrictive Fluid Resuscitation in Piglets with Pulmonary or Extrapulmonary Acute Respiratory Distress Syndrome.Medical science monitor : international medical journal of experimental and clinical research · 2015Article
- Noninvasive biomagnetic detection of intestinal slow wave dysrhythmias in chronic mesenteric ischemia.American journal of physiology. Gastrointestinal and liver physiology · 2015Article
- Gastrointestinal ischemia monitoring through impedance spectroscopy as a tool for the management of the critically ill.Experimental biology and medicine (Maywood, N.J.) · 2015Review
- Man is the new mouse: Elective surgery as a key translational model for multi-organ dysfunction and sepsis.Journal of the Intensive Care Society · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An association between abnormal gastrointestinal perfusion and critical illness has been suggested for a number of years. Much of the data to support this idea comes from studies using gastric tonometry. Although an attractive technology, the interpretation of tonometry data is complex. Furthermore, current understanding of the physiology of gastrointestinal perfusion in health and disease is incomplete. This review considers critically the striking clinical data and basic physiological investigations that support a key role for gastrointestinal hypoperfusion in initiating and/or perpetuating critical disease.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.