ReviewArthritis research2000
Death, autoantigen modifications, and tolerance.
Review in Arthritis research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 150 citations in OpenAlex.
- Post-Translational Modifications Modulate the HLA-DR3 Restricted Epitope Landscape of Sjögren's Associated Autoantigens.Medicina (Kaunas, Lithuania) · 2026Article
- Implications of Post-Translational Modifications in Autoimmunity with Emphasis on Citrullination, Homocitrullination and Acetylation for the Pathogenesis, Diagnosis and Prognosis of Rheumatoid Arthritis.International journal of molecular sciences · 2022Review
- 14-3-3ζ: A suppressor of inflammatory arthritis.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Extracellular vesicles and lupus nephritis - New insights into pathophysiology and clinical implications.Journal of autoimmunity · 2020Review
- ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease.Scientific reports · 2018Article
- Effects of type II collagen epitope carbamylation and citrullination in human leucocyte antigen (HLA)-DR4(+) monozygotic twins discordant for rheumatoid arthritis.Clinical and experimental immunology · 2016Article
- Myelin Basic Protein Citrullination in Multiple Sclerosis: A Potential Therapeutic Target for the Pathology.Neurochemical research · 2016Review
- The clinical significance of posttranslational modification of autoantigens.Clinical reviews in allergy & immunology · 2014Review
- The pathogenesis and diagnosis of systemic lupus erythematosus: still not resolved.Seminars in immunopathology · 2014Review
- Article
- Coherent somatic mutation in autoimmune disease.PloS one · 2014Review
- Epigenetics of autoantigens: new opportunities for therapy of autoimmune diseases.Genetics & epigenetics · 2013Review
- Felty's syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps.Arthritis and rheumatism · 2012Article
- Autoantigenesis: the evolution of protein modifications in autoimmune disease.Current opinion in immunology · 2012Review
- NETs: the missing link between cell death and systemic autoimmune diseases?Frontiers in immunology · 2012Article
- Proteins derived from neutrophil extracellular traps may serve as self-antigens and mediate organ damage in autoimmune diseases.Frontiers in immunology · 2012Article
- Autoimmune dysregulation and purine metabolism in adenosine deaminase deficiency.Frontiers in immunology · 2012Article
- Are Toll-like receptors and decoy receptors involved in the immunopathogenesis of systemic lupus erythematosus and lupus-like syndromes?Clinical & developmental immunology · 2012Review
- Inhibitors of MAPK pathway ERK1/2 or p38 prevent the IL-1{beta}-induced up-regulation of SRP72 autoantigen in Jurkat cells.The Journal of biological chemistry · 2010Article
- Epigenetic histone code and autoimmunity.Clinical reviews in allergy & immunology · 2010Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Autoantibodies present in the serum of patients with a variety of inflammatory diseases have proven useful as diagnostic markers and as probes with which to elucidate biochemical and signaling pathways. The mechanisms governing the generation of autoantibodies remain elusive, constituting a critical missing link in our understanding of rheumatologic illnesses. Several lines of experimentation in recent years have strongly implicated events surrounding cell death in this process. This review will address the potential role played by death-specific modifications of autoantigens in bypassing tolerance to highly conserved autoantigens, including nucleic acids, lipids, and proteins.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.