ArticleAntimicrobial agents and chemotherapy2000
Antiretroviral agents inhibit infection of human cells by porcine endogenous retroviruses.
Article in Antimicrobial agents and chemotherapy, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 39 citations in OpenAlex.
- Do Antiretroviral Drugs Protect From Multiple Sclerosis by Inhibiting Expression of MS-Associated Retrovirus?Frontiers in immunology · 2018Trial
- Characterization of porcine endogenous retrovirus insertion in Jeju native pigs and commercial breeds.Animal bioscience · 2025Article
- Surveillance and prevention of infection in clinical xenotransplantation.Clinical microbiology reviews · 2025Review
- Virus Safety of Xenotransplantation.Viruses · 2022Review
- Review
- How the COVID-19 pandemic may impact public support for clinical xenotransplantation in the United States?Xenotransplantation · 2020Review
- Infection in xenotransplantation: opportunities and challenges.Current opinion in organ transplantation · 2019Review
- Can Antiretroviral Drugs Be Used to Treat Porcine Endogenous Retrovirus (PERV) Infection after Xenotransplantation?Viruses · 2017Review
- Susceptibility of porcine endogenous retrovirus to anti-retroviral inhibitors.Xenotransplantation · 2016Article
- Infection barriers to successful xenotransplantation focusing on porcine endogenous retroviruses.Clinical microbiology reviews · 2012Review
- Restriction of porcine endogenous retrovirus by porcine APOBEC3 cytidine deaminases.Journal of virology · 2011Article
- Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates.Antimicrobial agents and chemotherapy · 2007Article
- Evaluation of endogenous pig retrovirus expression and of tumorigenicity in nude mice.Veterinary research communications · 2004Article
- Intracellularly expressed single-domain antibody against p15 matrix protein prevents the production of porcine retroviruses.Journal of virology · 2003Article
- Characterization of endogenous retroviruses in pig cell cultures.Veterinary research communications · 2003Article
- Transcriptional regulation of porcine endogenous retroviruses released from porcine and infected human cells by heterotrimeric protein complex NF-Y and impact of immunosuppressive drugs.Journal of virology · 2002Article
- Molecular and enzymatic characterization of the porcine endogenous retrovirus protease.Journal of virology · 2002Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The efficacy of antiretroviral drugs against porcine endogenous retroviruses (PERV) that may be harbored in pig organs intended for transplantation was examined in human cells in vitro. The nucleoside analogs zidovudine and dideoxyinosine were found to effectively inhibit PERV replication.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.