ArticleBone marrow transplantation2000
Crohn's disease complicated by relapsed extranodal Hodgkin's lymphoma: prolonged complete remission after unmanipulated PBPC autotransplant.
Article in Bone marrow transplantation, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 41 citations in OpenAlex.
- The Complex Relationship between Mechanisms Underlying Inflammatory Bowel Disease, Its Treatment, and the Risk of Lymphomas: A Comprehensive Review.International journal of molecular sciences · 2024Review
- Hematopoietic Stem Cell Transplantation in Refractory Crohn's Disease: Should It Be Considered?Cells · 2022Review
- Mesenchymal (Stem) Stromal Cells Based as New Therapeutic Alternative in Inflammatory Bowel Disease: Basic Mechanisms, Experimental and Clinical Evidence, and Challenges.International journal of molecular sciences · 2022Review
- Medical, ethical, and legal aspects of hematopoietic stem cell transplantation for Crohn's disease in Brazil.World journal of stem cells · 2020Review
- Umbilical cord blood mononuclear cell therapy induces clinical remission of steroid-dependent or -resistant ulcerative colitis patients.Oncotarget · 2018Article
- Stem cell therapy for inflammatory bowel disease.Journal of gastroenterology · 2015Review
- Therapy with stem cells in inflammatory bowel disease.World journal of gastroenterology · 2014Review
- Stem cell therapeutics: potential in the treatment of inflammatory bowel disease.Clinical and experimental gastroenterology · 2010Article
- Inflammatory bowel disease: Moving toward a stem cell-based therapy.World journal of gastroenterology · 2008Review
- Hematopoietic cell transplantation for Crohn's disease; is it time?World journal of gastroenterology · 2006Review
- Complete remission of Crohn's disease after high-dose cyclophosphamide and autologous stem cell transplantation.Bone marrow transplantation · 2003Article
- Clinically demonstrable anti-autoimmunity mediated by allogeneic immune cells favorably affects outcome after stem cell transplantation in human autoimmune diseases.Bone marrow transplantation · 2002Article
- Induction of tolerance in autoimmune diseases by hematopoietic stem cell transplantation: getting closer to a cure?International journal of hematology · 2002Review
- PBSC autotransplant for inflammatory bowel disease (IBD): a case of ulcerative colitis.Bone marrow transplantation · 2001Article
- A review of hematopoietic stem cell transplantation for autoimmune diseases: multiple sclerosis, systemic sclerosis and Crohn's disease. Position paper of the Brazilian Society of Bone Marrow Transplantation.Hematology, transfusion and cell therapyReview
- Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models.Mutation researchReview
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Crohn's disease and ulcerative colitis are inflammatory bowel diseases (IBD), which are thought to result from an inappropriate immunologic (autoimmune) response to luminal antibodies. Allogeneic stem cell transplantation (SCT) performed for coincidental diseases is able to cure both leukaemia and Crohn's disease. Autologous SCT is currently performed worldwide for severe autoimmune diseases (SADs) because of its reduced transplant-related mortality (TRM). We report the case of a 30-year-old male patient with a 10-year history of severe Crohn's disease, who developed Hodgkin's disease and received an unmanipulated peripheral blood autologous transplant. Three years after the transplant the patient is in complete treatment-free remission of both diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.