ArticlePituitary1999
Invasive pituitary adenomas: significance of proliferation parameters.
Article in Pituitary, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Intraoperative optical identification of pituitary adenomas.Journal of neuro-oncology · 2009Trial
- Differential expression of cyclin D1 in pituitary neuroendocrine tumours: Relation to aggressive potential.African journal of laboratory medicine · 2026Article
- Invasive pituitary adenoma presenting with cerebrospinal fluid rhinorrhea and meningitis - A case report.Surgical neurology international · 2024Article
- Pituitary Carcinoma Diagnosis and Survival Improvement, with Affordable Care Act Correlation: A SEER Database Study.Journal of neurological surgery. Part B, Skull base · 2022Article
- Genomics and Epigenomics of Pituitary Tumors: What Do Pathologists Need to Know?Endocrine pathology · 2021Review
- Transcriptomic analysis identifies a tumor subtype mRNA classifier for invasive non-functioning pituitary neuroendocrine tumor diagnostics.Theranostics · 2021Article
- Are aggressive pituitary tumors and carcinomas two sides of the same coin? Pathologists reply to clinician's questions.Reviews in endocrine & metabolic disorders · 2020Review
- Review
- Malignant transformation in non-functioning pituitary adenomas (pituitary carcinoma).Pituitary · 2018Review
- Pituitary carcinoma: A case report and discussion of potential value of combined use of Ga-68 DOTATATE and F-18 FDG PET/CT scan to better choose therapy.Surgical neurology international · 2017Article
- Article
- Multiple intracranial and spinal metastases from a nonfunctioning pituitary adenoma following multiple surgeries: an illustrative case with 16 years of follow-up.World journal of surgical oncology · 2014Article
- In search of a prognostic classification of endocrine pituitary tumors.Endocrine pathology · 2014Review
- Management of aggressive pituitary adenomas and pituitary carcinomas.Journal of neuro-oncology · 2014Review
- A 28 year old lady with a pituitary mass.Brain pathology (Zurich, Switzerland) · 2012Article
- Cell proliferation parameters and apoptosis indices in pituitary macroadenomas.Journal of endocrinological investigation · 2012Article
- Clinical review: Pituitary carcinoma: difficult diagnosis and treatment.The Journal of clinical endocrinology and metabolism · 2011Review
- My approach to pathology of the pituitary gland.Journal of clinical pathology · 2006Review
- DNA-flow cytometry of 207 pituitary adenomas: ploidy, proliferation, and prognosis.Journal of endocrinological investigation · 2005Article
- Cyclins D1 and D3 and topoisomerase II alpha in inactive pituitary adenomas.Endocrine pathology · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although most pituitary adenomas behave in a purely benign fashion, microscopic invasion of the subjacent dura is very common, and clinically overt infiltration of the surrounding dura and bone is apparent at intraoperative inspection in about one third of cases. The factors governing invasive behavior remain unknown but are believed to be separate from those regulating cell proliferation. Histological features alone do not distinguish between benign, invasive, and malignant tumors of adenohypophyseal origin. Multiple attempts have been made to identify prognostic markers of aggressive behavior among these tumors. They include cytogenetic analysis of putative tumor suppressor genes or proto-oncogenes as well as immunohistochemical detection of cell-cycle specific antigens. At present, however, these analyses can neither distinguish the indolent pituitary adenoma from one that will pursue an invasive course, nor reliably predict the prognosis in individual patients.
Indexed as
Identifiers
11081161What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.