ArticleGenome research2000
BodyMap: a collection of 3' ESTs for analysis of human gene expression information.
Article in Genome research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- FANTOM5 transcriptome catalog of cellular states based on Semantic MediaWiki.Database : the journal of biological databases and curation · 2016Article
- ToppMiR: ranking microRNAs and their mRNA targets based on biological functions and context.Nucleic acids research · 2014Article
- A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages.Nature communications · 2014Article
- Review: Alternative Splicing (AS) of Genes As An Approach for Generating Protein Complexity.Current genomics · 2013Article
- The expression of embryonic liver development genes in hepatitis C induced cirrhosis and hepatocellular carcinoma.Cancers · 2012Article
- Genomics and bioinformatics resources for crop improvement.Plant & cell physiology · 2010Review
- Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method.DNA research : an international journal for rapid publication of reports on genes and genomes · 2008Article
- Intron Evolution and Information processing in the DNA polymerase alpha gene in spirotrichous ciliates: a hypothesis for interconversion between DNA and RNA deletion.Biology direct · 2007Article
- ECgene: genome-based EST clustering and gene modeling for alternative splicing.Genome research · 2005Article
- Integrative annotation of 21,037 human genes validated by full-length cDNA clones.PLoS biology · 2004Article
- Methods for transcriptional profiling in plants. Be fruitful and replicate.Plant physiology · 2004Review
- Identification of alternatively spliced mRNA variants related to cancers by genome-wide ESTs alignment.Oncogene · 2004Article
- Annotation and analysis of 10,000 expressed sequence tags from developing mouse eye and adult retina.Genome biology · 2003Article
- A two-step strategy for constructing specifically self-subtracted cDNA libraries.Nucleic acids research · 2002Article
- The human ribosomal protein genes: sequencing and comparative analysis of 73 genes.Genome research · 2002Article
- Establishment of a high throughput EST sequencing system using poly(A) tail-removed cDNA libraries and determination of 36,000 bovine ESTs.Nucleic acids research · 2001Article
Corrections and comments
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Authors and funding
26 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BodyMap is a collection of site-directed 3' expressed sequence tags (ESTs) (gene signatures, GSs) that contains the transcript compositions of various human tissues and was the first systematic effort to acquire gene expression data. For the construction of BodyMap, cDNA libraries were made, preserving abundance information and histologic resolutions of tissue mRNAs. By sequencing 164,000 randomly selected clones, 88,587 GSs that represent chromosomally coded transcripts have been collected from 51 human organs and tissues. They were clustered into 18,722 independent 3' termini from transcripts, and more than 3000 of these were not found among ESTs assembled in UniGene (Build 75). Assessment of the prevalence of polyadenylation signals and comparison with GenBank cDNAs indicated that there was no significant contamination by internally primed cDNAs or genomic fragments but that there was a relatively high incidence (12%) of alternative polyadenylation sites. We evaluated the sensitivity and resolution of expression information in BodyMap by in silico Northern hybridization and selection of tissue-specific gene probes. BodyMap is a unique resource for estimation of the absolute abundance of transcripts and selection of gene probes for efficient hybridization-based gene expression profiling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.