ArticleBritish journal of cancer2000
Gene expression profiles in thyroid carcinomas.
Article in British journal of cancer, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gene Expression (mRNA) Markers for Differentiating between Malignant and Benign Follicular Thyroid Tumours.International journal of molecular sciences · 2017Pooled it
- Functional polymorphisms in antioxidant genes in Hurthle cell thyroid neoplasm - an association of GPX1 polymorphism and recurrent Hurthle cell thyroid carcinoma.Radiology and oncology · 2016Article
- Secreted protein acidic and rich in cysteine (SPARC) is associated with nasopharyngeal carcinoma metastasis and poor prognosis.Journal of translational medicine · 2012Article
- Advances in cellular therapy for the treatment of thyroid cancer.Journal of oncology · 2010Article
- Article
- Proteomic analysis of human thyroid cell lines reveals reduced nuclear localization of Mn-SOD in poorly differentiated thyroid cancer cells.Journal of endocrinological investigation · 2005Article
- Overexpression of SPARC gene in human gastric carcinoma and its clinic-pathologic significance.British journal of cancer · 2004Article
- High-throughput differential screening of mRNAs by serial analysis of gene expression: decreased expression of trefoil factor 3 mRNA in thyroid follicular carcinomas.British journal of cancer · 2004Article
- A preoperative diagnostic test that distinguishes benign from malignant thyroid carcinoma based on gene expression.The Journal of clinical investigation · 2004Article
- Proteomic and postproteomic characterization of keratan sulfate-glycanated isoforms of thyroglobulin and transferrin uniquely elaborated by papillary thyroid carcinomas.The American journal of pathology · 2003Article
- Analysis of gene expression profile of pancreatic carcinoma using cDNA microarray.World journal of gastroenterology · 2003Article
- New molecular methods for classification, diagnosis and therapy prediction of hematological malignancies.Pathology oncology research : POR · 2002Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gene expression profiles of human thyroid carcinomas were analysed by serial analysis of gene expression (SAGE) which allows quantitative and simultaneous analysis of a large number of transcripts. More than 29,000 transcripts derived from a normal thyroid tissue and four thyroid tumours were analysed. While extensive similarity was noted between the expression profiles of the normal thyroid tissue and three differentiated thyroid tumours, many transcripts, such as osteonectin, a-tubulin, glyceraldehyde-3-phosphate dehydrogenase, glutathione peroxidase, and thyroglobulin, were expressed at extremely different levels in differentiated and undifferentiated carcinomas. These data provide new information that might be used to identify genes useful for the diagnosis and treatment of thyroid carcinomas.
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Registered trials
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