Evidence map›Paper›PMID 11060049›Full record

ArticleJournal of clinical microbiology2000

Results of a quality assurance program for detection of cytomegalovirus infection in the pediatric pulmonary and cardiovascular complications of vertically transmitted human immunodeficiency virus infection study.

G J Demmler, A Istas, K A Easley, A Kovacs

Registry-linked trialOpen access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Journal of clinical microbiology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00005274 (Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00005274 completednot on this map

Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection (P2C2)

TypeobservationalSponsorNational Heart, Lung, and Blood Institute (NHLBI)Ran1989 to 2003ConditionsAcquired Immunodeficiency Syndrome, Lung Diseases, Cardiovascular Diseases, Heart Diseases
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

G J DemmlerDepartments of Pediatrics, Baylor College of Medicine, Houston, Texas, USA. gdemmler@bcm.tmc.edu
A Istas
K A Easley
A Kovacs
Pediatrics and Genetics · USCleveland Foundation · USLos Angeles Medical Center · US

Funding

ZOPOLRESTAT IN NORMOTENSIVE, TYPE 1 DIA WITH INCIPIENT NEPHROPATHYM01RR000043 · NCRR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ZAIA, JOHN A · 1985 to 2010
$76.4M
ZDV &3TC NEVIRAPINE COMBINATION THERAPY IN HIV 1 INFECTED INFANTS &M01RR000865 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WASHINGTON, ARNOLD E. · 1985 to 2011
$43.4M
ZIPRASIDONE (GEODON) AUGMENTATION IN SEROTONIN REUPTAKE INHIBITOR-RESISTANT OBM01RR000071 · NCRR · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI NEWCORN, JEFFREY H · 1985 to 2009
$41.5M
ZOLENDRONIC ACID IN CHILDREN W/ SEVERE OSTEOGENESIS IMPERFECTAM01RR000188 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI SHEARER, WILLIAM THOMAS · 1985 to 2011
$30.6M
ZOLEDRONIC ACID IN PROSTATE CANCERM01RR000645 · NCRR · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI COLTEN, HARVEY R · 1985 to 2006
$27.0M
WIRELESS CAPSULE ENDOSCOPY TO EVALUATE THE SMALL INTESTINE M01RR002172 · NCRR · CHILDREN'S HOSPITAL BOSTON · PI MANDELL, JAMES WILLIAM · 1985 to 2008
$16.0M
SIGNALING &METABOLIC ROLES OF GLUCOSE IN SPERMK01RR000188 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI TRAVIS, ALEXANDER J · 2000 to 2004
$589k
STUDY OF PEDIATRIC LUNG &HEART COMPLICATIONS OF HIVN01HR096037 · HR · CLEVELAND CLINIC FOUNDATION · 1989 to 2003
$315k
PEDIATRIC LUNG &HEART COMPLICATIONS OF HIV INFECTIONN01HR096038 · HR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KAPLAN, SAMUEL L · 1989 to 2000
–
PEDIATRIC LUNG AND COMPLICATIONS OF HIV INFECTIONN01HR096039 · HR · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI TEITEL, DAVID F · 1989 to 1990
–
PEDIATRIC LUNG &HEART COMPLICATIONS OF HIV INFECTIONN01HR096043 · HR · COLUMBIA PRESBYTERIAN MEDICAL CENTER · PI MELLINS, ROBERT B · 1989 to 2000
–
NCRR NIH HHS K01 RR000188NCRR NIH HHS M01 RR000043NCRR NIH HHS M01 RR000071NCRR NIH HHS M01 RR000188NCRR NIH HHS M01 RR000645NCRR NIH HHS M01 RR000865NCRR NIH HHS M01 RR002172NHLBI NIH HHS N01 HR096037NHLBI NIH HHS N01 HR096043NHLBI NIH HHS N01HR96037NHLBI NIH HHS N01HR96038NHLBI NIH HHS N01HR96039
6 · The paper itself

Abstract

A quality assurance program was established by the Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted Human Immunodeficiency Virus Type 1 Infection Study Group for monitoring cytomegalovirus (CMV) antibody and culture results obtained from nine different participating laboratories. Over a 3-year period, every 6 months, each laboratory was sent by the designated reference laboratory six coded samples: three urine samples for CMV detection and three serum samples for CMV immunoglobulin G (IgG) and IgM antibody determination. Overall, the participating laboratories exhibited the following composite performance statistics, relative to the reference laboratory (sensitivity and specificity, respectively): 100 and 97.4% for CMV cultures, 95.5 and 94.4% for CMV IgG antibody assays, and 92.6 and 90.2% for CMV IgM assays. The practice of having individual laboratories use different commercial methods and reagents for CMV detection and antibody determination was successfully monitored and provided useful information on the comparable performance of different assays.

Indexed as

Infectious Disease Transmission, VerticalAIDS-Related Opportunistic InfectionsAntibodies, ViralCardiovascular DiseasesChild, PreschoolCytomegalovirusCytomegalovirus InfectionsFemaleHIV InfectionsHumansImmunoenzyme TechniquesInfantInfant, NewbornLaboratoriesPediatricsPregnancyAntibodies, Viral

Identifiers

PMID11060049
PMCPMC87522
OpenAlexW2162913320

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.