ArticleNucleic acids research2000
Molecular characterisation of RecQ homologues in Arabidopsis thaliana.
Article in Nucleic acids research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 84 citations in OpenAlex.
- Repair of DNA double-strand breaks in plant meiosis: role of eukaryotic RecA recombinases and their modulators.Plant reproduction · 2023Review
- Review
- LSD1-LIKE1-Mediated H3K4me2 Demethylation Is Required for Homologous Recombination Repair.Plant physiology · 2019Article
- RecQ Helicases Function in Development, DNA Repair, and Gene Targeting inThe Plant cell · 2018Article
- G Quadruplex in Plants: A Ubiquitous Regulatory Element and Its Biological Relevance.Frontiers in plant science · 2017Review
- Identification and in silico analysis of cattle DExH/D box RNA helicases.SpringerPlus · 2016Article
- DNA damage and repair in plants - from models to crops.Frontiers in plant science · 2015Review
- Defining the roles of the N-terminal region and the helicase activity of RECQ4A in DNA repair and homologous recombination in Arabidopsis.Nucleic acids research · 2014Article
- A fluorescence-based exonuclease assay to characterize DmWRNexo, orthologue of human progeroid WRN exonuclease, and its application to other nucleases.Journal of visualized experiments : JoVE · 2013Article
- Sequence and expression analyses of KIX domain proteins suggest their importance in seed development and determination of seed size in rice, and genome stability in Arabidopsis.Molecular genetics and genomics : MGG · 2013Article
- RecQ helicases; at the crossroad of genome replication, repair, and recombination.Molecular biology reports · 2012Review
- Genome-wide comprehensive analysis of human helicases.Communicative & integrative biology · 2011Article
- RAD5A, RECQ4A, and MUS81 have specific functions in homologous recombination and define different pathways of DNA repair in Arabidopsis thaliana.The Plant cell · 2010Article
- Genome-wide analysis of helicase gene family from rice and Arabidopsis: a comparison with yeast and human.Plant molecular biology · 2010Article
- Biochemical characterization of AtRECQ3 reveals significant differences relative to other RecQ helicases.Plant physiology · 2009Article
- Computational identification of potential molecular interactions in Arabidopsis.Plant physiology · 2009Article
- News from Arabidopsis on the meiotic roles of Blap75/Rmi1 and Top3alpha.PLoS genetics · 2008Article
- A homolog of ScRAD5 is involved in DNA repair and homologous recombination in Arabidopsis.Plant physiology · 2008Article
- Identification of putative Arabidopsis DEMETER target genes by GeneChip analysis.Biochemical and biophysical research communications · 2007Article
- Two closely related RecQ helicases have antagonistic roles in homologous recombination and DNA repair in Arabidopsis thaliana.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Members of the RecQ family of DNA helicases are involved in processes linked to DNA replication, DNA recombination and gene silencing. RecQ homologues of various animals have been described recently. Here, for the first time for plants, we characterised cDNAs of all in all six different RecQ-like proteins that are expressed to different extents in Arabidopsis thaliana. Surprisingly, three of these proteins are small in size [AtRecQl1, AtRecQl2, AtRecQl3-606, 705 and 713 amino acids (aa), respectively], whereas the two bigger proteins result from a duplication event during plant evolution [AtRecQl4A and AtRecQl4B-1150 and 1182 aa, respectively]. Another homologue (AtRecQsim, 858 aa) most probably arose by insertion of an unrelated sequence within its helicase domain. The presence of these homologues demonstrates the conservation of RecQ family functions in higher eukaryotes. We also detected a small gene (AtWRNexo) encoding 285 aa which, being devoid of any RecQ-like helicase domain, reveals a striking homology to the exonuclease domain of human Werner protein, a prominent RecQ helicase of larger size. By means of the two-hybrid assay we were able to detect an interaction between AtWRNexo and AtRecQl2, indicating that activities that reside in a single protein chain in mammals might in plants be complemented in trans.
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