ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2000
Developmental changes in eye-blink conditioning and neuronal activity in the inferior olive.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Role of the motor cortex in the generation of classically conditioned eyelid and vibrissae responses.Scientific reports · 2021Article
- Article
- Sleep deprivation directly following eyeblink-conditioning impairs memory consolidation.Neurobiology of learning and memory · 2020Article
- Cannabinoid modulation of memory consolidation within the cerebellum.Neurobiology of learning and memory · 2016Article
- Climbing fibers encode a temporal-difference prediction error during cerebellar learning in mice.Nature neuroscience · 2015Article
- Cerebellar learning mechanisms.Brain research · 2015Review
- Cerebellar inhibitory output shapes the temporal dynamics of its somatosensory inferior olivary input.Cerebellum (London, England) · 2014Article
- Neuronal correlates of cross-modal transfer in the cerebellum and pontine nuclei.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Selective developmental increase in the climbing fiber input to the cerebellar interpositus nucleus in rats.Behavioral neuroscience · 2004Article
- Developmental changes in the neural mechanisms of eyeblink conditioning.Behavioral and cognitive neuroscience reviews · 2004Article
- The effects of ethanol on the developing cerebellum and eyeblink classical conditioning.Cerebellum (London, England) · 2004Review
- Addition of inhibition in the olivocerebellar system and the ontogeny of a motor memory.Nature neuroscience · 2003Article
- Developmental changes in eyeblink conditioning and neuronal activity in the pontine nuclei.Learning & memory (Cold Spring Harbor, N.Y.)Article
- Ontogenetic changes in the neural mechanisms of eyeblink conditioning.Integrative physiological and behavioral science : the official journal of the Pavlovian SocietyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Neuronal activity was recorded in the dorsal accessory inferior olive in infant rats during classical conditioning of the eye-blink response. The percentage and amplitude of eye-blink conditioned responses (CRs) increased as a function of age. The magnitude of the neuronal response to the unconditioned stimulus (US) decreased with age. There were also age-specific modifications of US-elicited inferior olive neuronal activity during paired trials in which a conditioned eye-blink response was performed. The results indicate that the development of the conditioned eye-blink response may depend on dynamic interactions between multiple developmental processes within the eye-blink circuitry. Differences in the functional maturity of olivo-cerebellar pathways may limit the induction of plasticity in the cerebellum and thereby limit the development of eye-blink conditioned responses.
Indexed as
Identifiers
11050145PMC6772727What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.